Abstract

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Title:: Medical imaging properties of tissue equivalent material of polyvinyl chloride

Author(s):: HE Yaoyao1; 2; 3; WANG Liwen4; SUN Zhe1; 2; 3; XU Zhikang1; 2; 3; ZHENG Fenglian1; 2; 3; SHI Liting1; 2; 3; YUAN Zilong5; SUN Yong3; QIU Jianfeng1; 2; 3; 1. Medical Engineering and Technology Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai’an 271016, China; 2. Imaging-X Joint Laboratory, Tai’an, 271016, China; 3. Department of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai’an 271016, China; 4. Guangzhou Institute of Measurement and Testing Technology, Guangzhou 510016, China; 5. Department of Radiology, Hubei Cancer Hospital, Wuhan 430079, China

Keywords:: ; Keywords: polyvinyl chloride; tissue equivalent material; CT number; MRI relaxation time; X-ray attenuation coefficient

Abstract:: Abstract: Objective Polyvinyl chloride (PVC) which had similar optical transparency and hardness with those of human tissues is suitable for medical applications as tissue equivalent materials. The purpose of this study is to investigate the relationships between different PVC-softener (dioctyl terephthalate, DOTP) mixture ratios and the medical imaging characteristics (such as X-ray attenuation coefficient, CT number and MRI relaxation time). Methods The medical imaging properties of the materials were affected by different PVC-DOTP mixture ratios. Therefore, 11 groups of PVC samples with different mixture ratios were prepared in the study. The medical imaging properties of PVC materials were evaluated by measuring the CT number and MRI relaxation time of PVC samples. Meanwhile, the X-ray attenuation coefficients of 5 groups of PVC samples at different voltages were also measured. Results When the PVC-DOTP mixture ratio ranged from 8.0×10-2 to 23.3×10-2 g/mL, the corresponding average CT number was -0.6 to 109.0 HU, and the T1 and T2 relaxation time was 172.3-203.9 ms and 13.7-32.1 ms, respectively. At the voltage of 40-120 kV, the X-ray attenuation coefficient of the samples was 6.0-20.8 m-1. Conclusion PVC which has controllable CT number and MRI relaxation time, with the advantages of good light transmittance and a certain degree of viscoelasticity, can be used as the tissue equivalent material for medical phantom.