Abstract

Info

Title:: Research progress on bone marrow mesenchymal stem cells in basic medicine and clinical application

Author(s):: LI Ting1; CHEN Lizhi1; HUANG Wenhua1; 2; 1. National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China; 2. Guangdong Province Medical 3D Printing Application Transformation Engineering Technology Research Center, Guangzhou 510515, China

Keywords:: ; Keywords: bone marrow mesenchymal stem cells; inducing differentiation; culture isolation; clinical application; basic research

Abstract:: Abstract: Bone marrow mesenchymal stem cells (BMSCs) which are an important member of stem cell family have the excellent biological characteristics of self-renewal, reproduction, multiplication and multi-differentiation. Since the 20th century, because of its special biological characteristics, BMSCs has been widely used in basic medicine and clinical application, and many significant progresses have been made. Herein the research progresses on the biological characteristics, isolation and culture, basic scientific researches and clinical applications of BMSCs are reviewed. The treatments of orthopedic diseases, cardiovascular diseases, liver cirrhosis and intervertebral disc degeneration with BMSCs are mainly introduced. The applications of BMSCs in basic medicine and clinical treatment are further explored through the review of the treatment strategies and techniques, thereby providing some references for the profound research on the basic scientific research and clinical application of BMSCs.