Abstract

Info

Title:: Simulation and design of an intelligent drug delivery driving device of electronic capsule

Author(s):: ZHANG Na1; GUO Xudong1; XU Tangcheng1; ZHANG Huihe1; WANG Jing2; 1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2. Jiangsu Apon Medical Technology Co., Ltd., Nantong 226400, China

Keywords:: ; Keywords: electronic capsule; driving device based on electromagnetic coil-double permanent magnet; multiple drug delivery; function relationship fitting; intelligent adjustment of driving force

Abstract:: Abstract: An intelligently adjustable drug delivery driving device based on electromagnetic coil-double permanent magnet is designed to realize the intelligent control of release dosage and release time of electronic capsules for gastrointestinal diseases. A mathematical model based on drug delivery driving force F, electromagnetic coil stroke d, and exciting current I is established to achieve controllable driving force. Moreover, a prototype of the drug delivery driving device is designed, and a platform for the test of drug delivery driving force is set up. The mathematical model of drug delivery driving force was established using Polynomial theory. The R2 (R-square) and root mean square error of the driving force model with different parameters were compared. When the highest power of I and d were chosen to be 1 power and 5 power, respectively, the fitting accuracy of the mathematical model is the best. According to the fitting model, the real-time excitation current of the electromagnetic coil was adjusted by excitation current adjustment module, so as to achieve the controllable release dosage and release time. The experimental verification showed that the driving force model is correct and feasible, providing a theoretical basis for the intelligent adjustment of drug delivery driving force.