Abstract

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Title:: Preliminary study of evaluating biomechanics with energy spectral computed tomography

Author(s):: HUANG Xiaoyu1; 2; XIE Qiqi1; 3; DENG Yajun1; 3; ZHAO Ruochen1; 4; DONG Qiang4; ZHOU Junlin1; 2; 1. Lanzhou University, Lanzhou 730030, China; 2. Department of Radiology, Second Hospital of Lanzhou University, Lanzhou 730030, China; 3. Department of Orthopedics, Second Hospital of Lanzhou University, Lanzhou 730030, China; 4. Department of Neurosurgery, Second Hospital of Lanzhou University, Lanzhou 730030, China

Keywords:: ; Keywords: energy spectrum computed tomography; osteoporosis; biomechanics; bone strength

Abstract:: Abstract: Objective To analyze the correlations between energy spectral computed tomography (CT) quantitative parameters and biomechanics, and explore the value of energy spectral CT quantitative parameters in the assessment of bone strength. Methods Energy spectral CT scanning was performed on 36 vertebral bodies to determine the density of CT-based material pairs (iron-water, calcium-water and hydroxyl-phosphorus) in cancellous, cortex and cortico-cancellous in each vertebral body of the sheep. Then the corresponding number of each vertebral body was removed, and lumbar compression experiment was conducted. The correlations between the density values of different pairs??(iron-water, calcium-water and hydroxyapatite-water) and the maximum load and maximum stress measured by biomechanics were analyzed. Results The analysis of the correlations between density values and biomechanical properties of energy spectral CT-based materials showed that for cortico-cancellous, calcium-water and hydroxyapatite-water were strongly correlated with the maximum stress (R2=0.508, P<0.05; R2=0.507, P<0.05), and moderately correlated with the maximum load (R2=0.454, P<0.05；R2=0.451, P<0.05), while the iron-water correlation was relatively lower. The 3 CT-based material pairs of cortex and cancellous had poor correlations between density values ??and biomechanical properties. Conclusion Energy spectral CT quantitative parameters can be used to evaluate bone strength.