Clinical value of energy spectrum CT for the differential diagnosis of pulmonary inflammatory lesion and lung cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第10期
- Page:
- 1164-1168
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Clinical value of energy spectrum CT for the differential diagnosis of pulmonary inflammatory lesion and lung cancer
- Author(s):
- WANG Jingjian; LI Na; WANG Longlong; GAO Yanzhong
- CT-MR Room, Ninth Hospital of Xi’an, Xi’an 710054, China
- Keywords:
- ; Keywords: energy spectrum CT; lung cancer; pulmonary inflammatory lesion; differential diagnosis; iodine concentration
- PACS:
- R445.3
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.10.010
- Abstract:
- Abstract: Objective To evaluate the value of energy spectrum computed tomography (CT) in differentially diagnosing lung inflammatory lesion and lung cancer. Methods A total of 85 patients with pulmonary space-occupying lesions were selected. All patients underwent energy spectrum CT plain scans, pulmonary artery and aortic scans. According to the pathological results, the patients were divided into lung cancer group and inflammatory lesion group. The iodine concentration (IC) of pulmonary arterial phase, IC of aortic phase, net increase of IC (dIC) of pulmonary artery phase, dIC of aortic phase, net increase of CT value (dCT) of pulmonary artery phase, dCT of aortic phase, and effective atomic number were compared between two groups. The diagnostic performance of different parameters was determined by receiver operating characteristic curve. Results Of the 85 patients, 52 patients were diagnosed with lung cancer and 33 were diagnosed with inflammatory lesions. IC of pulmonary arterial phase, IC of aortic phase, dIC of pulmonary artery phase, dIC of aortic phase, and dCT of pulmonary artery phase were significantly lower in patients with lung cancer as compared with those with inflammatory lesions (P<0.05). No statistical significance was found in dCT of aortic phase and effective atomic number between patients with pneumonia and those with inflammatory lesions (P>0.05). The dIC of pulmonary arterial phase had the greatest value in distinguishing lung cancer from inflammatory lesions, with a sensitivity of 0.966 and a standard error of only 0.027. Conclusion The IC value and CT value of energy spectrum CT are helpful for the differential diagnosis of inflammatory lesion and lung cancer, among which the dIC of pulmonary arterial phase has the greatest discriminative value.
Last Update: 2018-10-23