Factors affecting the passing rate of intensity-modulated radiotherapy plans(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第10期
- Page:
- 1117-1121
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Factors affecting the passing rate of intensity-modulated radiotherapy plans
- Author(s):
- GUO Ran1; ZHANG Yibao2; LI Minghui1; LI Yundong3; DAI Jianrong1
- 1. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China; 2. Department of Radiation Oncology, Peking University Cancer Hospital & Institute/Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Beijing 100142, China; 3. Jining NO.1 People’s Hospital, Jining 272011, China
- Keywords:
- ; Keywords: plan quality assurance; PTW 729 detector array; intensity-modulated radiotherapy
- PACS:
- R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.10.001
- Abstract:
- Abstract: Objective To investigate the factors which affects the passing rate of intensity-modulated radiotherapy (IMRT) plans. Methods A total of 68 static IMRT plans designed by Pinnacle treatment planning systems were selected. After all radiation fields were normalized to gantry angle 0°, the dose distributions were measured with PTW 729 chamber array and solid water phantom based on Synergy accelerator. Then PTW VeriSoft software was used to compare the differences between measured results and computed values. Using 3 mm/3% criteria, the Gamma passing rates of Local and Max were analyzed and compared. The correlations between the passing rate of Local and various factors, such as monitor unit, the number of segments, the mean area of segments and the coefficient of variation of segments area, were analyzed. Regression analysis was used to obtain the linear relationship between the passing rate and the affecting factors. Results The passing rates of Local were lower than those of Max for all plans (P<0.01). The passing rates of head and neck plans were significantly different from other sites, with statistical significances (P<0.01). The passing rates of Local had linear relationships with the treatment sites, the number of segments and the coefficient of variation of segments area. Conclusion The passing rate of Local is significantly lower than that of Max. Compared with plans for other sits, head and neck plan has a lower passing rate. The passing rates of Local can be preliminary estimated by monitor unit and the number of segment. Treatment sites, the number of segments and the coefficient of variation of segments area are the main factors that affect the passing rates of Local. Multiple linear regression equations can provide some guidance for the design and selection of optimal plans.
Last Update: 2018-10-22