Abstract

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Title:: Effects of extremely low frequency electromagnetic exposure on calcium ion transmembrane migration and mechanism analysis

Author(s):: ZHOU Yongjun1; ZHANG Hui1; NIU Zhongqi2; 1. School of Physics and Electronic Engineering, Xianyang Normal University, Xianyang 712000, China; 2. School of Electric Engineering, Xidian University, Xi’an 710071, China

Keywords:: ; Keywords: extremely low frequency electromagnetic exposure; calcium ion; transmembrane migration; influence; mechanism

Abstract:: Abstract: Objective To study the effects of extremely low frequency (ELF) electromagnetic exposure on calcium ion transmembrane migration. Methods The human hepatoma cells were taken as the subjects in this study. The responses of calcium ion transmembrane migration to ELF electromagnetic exposure were detected by laser scanning confocal microscopy. Results Under the condition that the magnetic field strength remained at 1.78×10-7 T, the transmembrane migration of calcium ion in exposure groups was responded to the applied electromagnetic exposure environment with different properties. With the frequency (f) of 16 Hz or 45 Hz and electric field peak (EP) of 53 V/m, f of 16 Hz and EP of 80 V/m, the ELF electromagnetic exposure made calcium ion transmembrane migration increased significantly, while calcium ion transmembrane migration wasn’t increased significantly under the exposure with f of 32 Hz or 60 Hz and EP of 53 V/m, f of 16 Hz and EP of 26 V/m or 87 V/m. Conclusion The combination of different frequencies and electric field peaks of ELF electromagnetic exposure can increase calcium ion transmembrane migration, and the differences are significant, which provides experimental basis for the biological application of ELF electromagnetic exposure. The mechanism of the effects of ELF electromagnetic exposure on calcium ion transmembrane migration should be discussed based on the physical and biological characteristics of cell membrane ion channels.