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Rigid registration of multimodal medical images based on mask optimization(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2018年第9期
Page:
1022-1029
Research Field:
医学影像物理
Publishing date:

Info

Title:
Rigid registration of multimodal medical images based on mask optimization
Author(s):
PI Yifei1 WU Qian2 PEI Xi1 XU Xie1
1. School of Physical Sciences, University of Science and Technology of China, Hefei 230026, China; 2. School of Medical Humanities, Anhui Medical University, Hefei 230032, China
Keywords:
medical image processing rigid registration mask multimodality
PACS:
R319;TP311.52
DOI:
10.3969/j.issn.1005-202X.2018.09.006
Abstract:
Abstract:Objective To develop a rigid registration program based on ITK and OpenCV and make it compatible with DeepPlan treatment planning system for achieving rapid and precise multimodality image registration. Methods Mathematical morphology analysis was used to erasure insignificant and tiny structures and partial scanning couch; Otsu filter was applied to further highlight the regions of interest; and Canny operators were utilized to extract edge information from regions rich in information. Then the mask required in image registration was obtained by pixel filling algorithm, and the pre-processing process was accelerated with OpenMP parallel strategy. Finally, the mask acted on the fixed image and moving image during registration. Results The proposed method was validated on clinical images datasets with different modalities and body parts, and the results revealed that the most interferential background image and scanning couch were removed by rigid registration of multimodal medical image based on mask optimization, saving more than more than half of the time while without degrading the image registration quality. The registration of two groups of about 100 images could be finished within 1 minute. The relative codes were also successfully integrated in DeepPlan treatment planning system in the form of dynamic-link library. Conclusion Rigid registration of multimodal medical image based on mask optimization improves the efficiency of image registration, without affecting registration accuracy, and the proposed algorithm is highly stable. Therefore, the proposed method has a good prospect in clinical application.

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Last Update: 2018-09-28