Value of dynamic contrast-enhanced MRI, ADC and 3D subtraction technique for the diagnosis of ovarian cystadenoma and cystadenocarcinoma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第5期
- Page:
- 573-579
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Value of dynamic contrast-enhanced MRI, ADC and 3D subtraction technique for the diagnosis of ovarian cystadenoma and cystadenocarcinoma
- Author(s):
- WU Mengnan1; 2; QUAU Xianyue1; HUANG Zhiming2; KE Canze2; LAI Dongping2
- 1. Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China; 2. Department of Radiology, Heyuan People’s Hospital, Heyuan 517000, China
- Keywords:
- ; Keywords: cystadenoma; cystadenocarcinoma; diffusion-weighted imaging; apparent diffusion coefficient; dynamic contrast-enhanced magnetic resonance imaging; three-dimensional subtraction technique
- PACS:
- R816.91
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.05.014
- Abstract:
- Abstract: Objective To explore the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (MRI), multiple b-value diffusion-weighted imaging (DWI) combined with apparent diffusion coefficient (ADC) and three-dimensional (3D) subtraction technique for ovarian cystadenoma and cystadenocarcinoma. Methods Thirty-nine cases of cystadenoma and 12 cases of cystadenocarcinoma confirmed by surgery and pathology received conventional MRI, multiple b-value DWI with ADC measurement of solid and cystic components, dynamic contrast-enhanced MRI, 3D subtraction multimodal scanning. The obtained data were retrospectively analyzed. Results Among 55 lesions, 40 of them were benign cystadenoma and the other 15 were cystadenocarcinoma. The conventional MRI revealed that among 51 selected cases, 9 cases had "stained-glass" sign and 6 cases of cystadenoma had isointensity wall nodules on T2-weighted image (T2WI). The b-value DWI was 100, 500, 1 000 mm2/s, respectively. The ADC values of solid and cystic components of ovarian cystadenocarcinoma were lower than those of ovarian cystadenoma, with significant differences (P<0.05). The ADC values of cystadenoma were (3.03±0.23)×10-3, (2.92±0.20)×10-3 and (2.88±0.21)×10-3 mm2/s, respectively, while those of cystic components of cystadenocarcinoma were (2.71±0.31)×10-3, (2.63±0.27)×10-3 and (2.47±0.41)×10-3 mm2/s, respectively. The ADC values of solid components of cystadenocarcinoma were (1.80±0.50)×10-3, (1.47±0.48)×10-3 and (1.30±0.39)×10-3 mm2/s, respectively. The dynamic contrast-enhanced MRI demonstrated that no enhancement or slightly enhancement on isointensity wall nodules on T2WI of cystadenoma, and the time-intensity curve (TIC) was type I. Moreover, the isointensity wall nodules and solid components in 13 cases of cystadenocarcinoma were significantly enhanced on T2WI, and the TIC was type II. The TIC of 2 borderline cystadenocarcinoma was type I. 3D subtraction scanning image showed enhancement characteristics at the arterial phase of wall nodules. No enhancement was found at thrombus and cell fragments. The nipple structure of cystadenoma was slightly enhanced but the wall nodules and solid component of cystadenocarcinoma were significantly enhanced. Conclusion The combined use of dynamic contrast-enhanced MRI, multiple b-value DWI and 3D subtraction technique is more valuable for the diagnosis of ovarian cystadenoma and cystadenocarcinoma.
Last Update: 2018-05-22