Dosimetric comparison of two postoperative radiotherapy techniques for seminoma based on Monte Carlo algorithm(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第8期
- Page:
- 905-908
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric comparison of two postoperative radiotherapy techniques for seminoma based on Monte Carlo algorithm
- Author(s):
- WANG Li1; 2; HE Chunlin1; ZHENG Xin1; CHEN Minzhi1; LAI Qingkuan1; REN Jie2
- 1. School of Computing, China West Normal University, Nanchong 637000, China; 2. Nanchong Central Hospital, Nanchong 637000, China
- Keywords:
- ; Keywords: seminoma; three-dimensional conformal radiotherapy; intensity-modulated radiotherapy; dosimetry; Monte Carlo algorithm
- PACS:
- R730.55；R737.9
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.08.008
- Abstract:
- Abstract: Objective To compare the dosimetric differences between two radiotherapy technologies based on Monte Carlo algorithm for siminoma after inguinal high testicle excision, and investigate the advantages of the two technologies in improving the target dose and protecting the organs-at-risk (OAR). Methods According to the localization images of 24 patients undergoing postoperative radiotherapy for seminoma, 2 plans were designed for each patient, namely three-dimensional conformal radiotherapy (3DCRT) plan and intensity-modulated radiotherapy (IMRT) plan, with 90% planning target volume receiving the prescription dose of 32.4 Gy/1.8 Gy/18 f. The differences in dosimetry parameters of target areas and OAR, and monitor units were compared and analyzed. Results The target conformability and homogeneity of IMRT plan were better than those of 3DCRT plan (P<0.05). The D2, V105%,V110% of target areas were lower in IMRT plan as compared with those in 3DCRT plan (P<0.05), while the D98 of target areas in 3DCRT plan was lower than that in IMRT plan (P<0.05). Several OAR dose parameters in IMRT plan were lower those in 3DCRT plan (P<0.05), including the Dmean, D2, V20 of spinal cord, the D98, V10, V20 of left kidney, the Dmean, D2, D98, V10, V20, V30 of right kidney, the Dmean, D2 of small bowel, the D98, V10 of bladder, and the Dmean, D98, V10, V20, V30 of femoral head. However, the Dmean, D2, V20, V30 of liver and the V20 of small bowel in 3DCRT plan were lower than those in IMRT plan (P<0.05). The average monitor units of 3DCRT plan and IMRT plan were 256 and 947 MU, respectively. Conclusion As adjuvant radiotherapy after inguinal high testicle excision for seminoma, both 3DCRT and IMRT meet the clinical needs. Compared with 3DCRT, IMRT has advantages in target dose distribution, and the protection of spinal cord, kidney, bladder and femoral head. However, 3DCRT has more advantages in protecting liver, while reducing monitor loss and work burden of technicians.
Last Update: 2018-07-26