Abstract

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Title:: Dose comparison of preoperative volumetric modulated arc therapy and dynamic intensity-modulated radiotherapy for cervical cancer

Author(s):: LI Ming; WANG Zhongming; ZHAO Jun; ZHOU Jie; MA Jianhua; Department of Radiotherapy, the Second People’s Hospital of Lianyungang, Lianyungang 222023, China

Keywords:: ; Keywords: cervical cancer; volumetric modulated arc therapy; dynamic intensity-modulated radiotherapy; monitor unit

Abstract:: Abstract: Objective To compare the dosimetric differences between volumetric modulated arc therapy (VMAT) and dynamic intensity-modulated radiotherapy (DIMRT) in preoperative radiotherapy for cervical cancer. Methods Ten patients receiving preoperative radiotherapy for cervical cancer were selected. After target areas were delineated, double-arc VMAT plan and 5-field DIMRT plan were designed with Eclipse 11.0 planning system. The conformity index and homogeneity index of target areas, dosimetric differences of organs-at-risk, monitor units and treatment time were compared. Results The conformity index and homogeneity index were similar in double-arc VMAT plan and 5-field DIMRT plan (0.78±0.05 vs 0.84±0.03, P>0.05; 0.05±0.00 vs 0.05±0.00, P>0.05). No significant differences were found in dosimetric indexes, except the V40, V45, V50 of bladder, the V20 of small intestine, the dose of femoral head and pelvis. Conclusion Both VMAT and DIMRT can meet the requirements of clinical dosimetry. VMAT is equivalent or superior to DIMRT in protecting normal organs. Moreover, VMAT technology has significant advantages in reducing monitor units and shortening treatment time.