Experimental study of cerebral hypoperfusion in hemorrhagic shock using magnetic induction phase shift method(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第6期
- Page:
- 707-713
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Experimental study of cerebral hypoperfusion in hemorrhagic shock using magnetic induction phase shift method
- Author(s):
- PAN Wencai1; CHONG Yinbao1; QIN Mingxin2; ZHUANG Wei2; MA Jieshi1; ZHAO Peng1
- 1. Department of Medical Engineering, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, China; 2. Department of Electronic Engineering, School of Biomedical Engineering, Army Medical University, Chongqing 400038, China
- Keywords:
- ; Keywords: magnetic induction phase shift; cerebral blood perfusion; hemorrhagic shock; arterial blood lactate; laser Doppler
- PACS:
- R318
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.06.016
- Abstract:
- Abstract: Magnetic induction phase shift (MIPS) technology which is based on the dielectric properties of biological tissues is a non-contact and noninvasive method for continuous monitoring. The feasibility of using MIPS for cerebral ischemia detection has been proved. In order to verify whether MIPS technology can effectively detect cerebral hypoperfusion in hemorrhagic shock, the cerebral hypoperfusion MIPS values of 20 rabbits with hemorrhagic shock were detected by homemade MIPS detection system, while the arterial blood lactate (ABL) and laser Doppler (LDF) values of the cerebral blood flow were used as references. The experimental data of 19 rabbits were selected for statistic analysis. The results revealed that with the development of hemorrhagic shock, the cerebral perfusion MIPS value reduced from the baseline (0°) to (-5.28±1.99)°; and that ABL concentration increased from (3.55±2.24) mmol/L to (13.34±6.66) mmol/L; and that the baseline percentage of cerebral blood flow LDF value decreases from 100% to (59.26±51.57)%. The cerebral perfusion MIPS value was proved to be highly correlated with ABL concentration, with all correlation coefficients greater than 0.816, and meanwhile MIPS measurement had better detection resolutions than LDF measurement. The above results show that the MIPS technology can effectively detect cerebral hypoperfusion in hemorrhagic shock. Using cerebral perfusion MIPS is feasible for pre-hospital hemorrhagic shock detection.
Last Update: 2018-06-22