Dosimetric comparison and analysis of volumetric modulated arc radiotherapy plan for cervical cancer based on Monaco system and Pinnacle system(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第6期
- Page:
- 654-658
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric comparison and analysis of volumetric modulated arc radiotherapy plan for cervical cancer based on Monaco system and Pinnacle system
- Author(s):
- BAI Han; CHEN Feihu; LI Wenhui; LI Lan; ZHU Sijin; LIU Xuhong
- The Third Affiliated Hospital of Kunming Medical University & Yunnan Tumor Hospital, Yunnan 650118, China
- Keywords:
- ; Keywords: cervical cancer; Monaco treatment planning system; Pinnacle treatment planning system; volumetric modulated arc radiotherapy; radiotherapy dose
- PACS:
- R730.55；R735.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.06.007
- Abstract:
- Abstract: Objective To compare and analyze the dose differences of volumetric modulated arc radiotherapy (VMAT) plan for cervical cancer based on Monaco treatment planning system (TPS) and Pinnacle TPS for exploring an optimal TPS to design cervical cancer VMAT plan. Methods Eleven cervical cancer patients receiving radical radiotherapy in Yunnan Tumor Hospital were selected. With the same location CT data, target areas and organs-at-risk, Monaco TPS and Pinnacle TPS were applied to design two VMAT plans for each patient, namely VMATMONACO plan and VMATPINNACLE plan. The dose distribution in target areas, conformity index, homogeneity index, and the dose-volume differences in organs-at-risk were compared. Finally, the advantage and disadvantage of two kinds of TPS in VMAT plan design were discussed and their causes were expounded. Results The differences in conformity index of PGTVnd and PTV didn’t showed any significances between VMATMONACO plan and VMATPINNACLE plans (P>0.05). For the homogeneity index of PGTVnd, VMATPINNACLE plan was superior to VMATMONACO plan, with statistical differences (P<0.05). No differences were found in the low-dose area of the rectum and bladder between VMATPINNACLE plan and VMATVMAT plan (P>0.05); in high-dose areas, VMATMONACO plan was better than VMATPINNACLE plan. The mean doses of the rectum and the bladder in VMATMONACO plan were lower than those in VMATPINNACLE plan, with statistical significance (P<0.01). Moreover, the dose of the small intestine and the femur head were lower in VMATMONACO plan as compared with VMATPINNACLE plan (P<0.05). Conclusion Using Monaco TPS instead of Pinnacle TPS to design radiotherapy plan for cervical cancer has potential dose advantages.
Last Update: 2018-06-22