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Application of multi-criteria plan quality assessment system in rectal cancer(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2018年第9期
Page:
1017-1021
Research Field:
医学放射物理
Publishing date:

Info

Title:
Application of multi-criteria plan quality assessment system in rectal cancer
Author(s):
HE Ruimin1;  QIU Xiaoping1;  YANG Zhen2;  CAO Ying2;  YANG Xiaoyu2;  XIAO Hao3
1. Nanhua University, Hengyang 421001, China; 2. Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China; 3. Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510000, China
Keywords:
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PACS:
1005-202X（2018）09-1017-05
DOI:
10.3969/j.issn.1005-202X.2018.09.005
Abstract:
Keywords: rectal cancer; intensity-modulated radiotherapy; Rapid arc; plan quality meObjective To analyze the dosimetric differences between two techniques for rectal cancer with an automatic plan assessment system, and to establish a basis for refining the automatic planning process. Methods Twenty cases of rectal cancer were selected. Intensity-modulated radiotherapy (IMRT) technique was applied in 10 cases and Rapid Arc technique in the other 10 cases. The planning data of patients were imported into PlanIQ software to create plan quality metrics based on RTOG protocol and TG report files. The criterions included target coverage, homogeneity index, conformity index, and the dosimetric indicators of femoral head, small intestine, bladder and other organs-at-risk. After the integration of plan quality metrics, a rectal cancer plan quality assessment system was established. The established assessment system was used to score each criterion and compare the corresponding dosimetric parameters. Results The target coverage and hot spot in Rapid arc group were better than those in IMRT group, with statistical significance. The organs-at-risk sparing in Rapid arc group was superior to IMRT group except small intestine, and the differences in the V45, Dmaxof small intestine, the V40, Dmax of femoral head, and the V40, V45 of bladder were statistically significant (P<0.05). No significant differences were found between the two groups in homogeneity index and conformity index (P>0.05). According to the final scores obtained by quality assessment system, Rapid arc was proved to be better than IMRT, and the differences in scores were statistically significant (P<0.05). Conclusion Multi-criteria plan quality assessment system can effectively evaluate programs, reduce the workload of program reviews, and provide a good source of data for the databases of automatic planning.trics

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Last Update: 2018-09-28