Abstract

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Title:: Three-dimensional dose verification of intensity-modulated radiotherapy after left breast-conserving surgery

Author(s):: ZHOU Hui; XU Cheng; SHEN Wentong; CHEN Yi; ZHANG Yibin; Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200025, China

Keywords:: ; breast cancer; intensity-modulated radiotherapy; three-dimensional dose verification; Compass system

Abstract:: Abstract: Radiotherapy planning verification can ensure that patients receive accurate treatment. We performed Compass three-dimensional dose verification for intensity-modulated radiotherapy (IMRT) plans for 11 patients undergoing breast-conserving surgery for left breast cancer. The dose-volume histograms and Gamma values of the planning target volume (PTV) and the organs-at-risk (OAR) were analyzed by comparing the parameters in Compass reconstruction plan with those in Pinnacle treatment planning system. The results showed that the deviation of[ D1], [D95], [D99], and[ Dmean] of PTV and OAR were less than 1 Gy, and that of [V5, V20]and[ V30] were less than 1.5%. Under the 3 mm/3% criterion, the average Gamma value of PTV was 0.45±0.04, and the average passing rate was 92.70%±2.44%, which had a statistical significance; for OAR, the passing rate was nearly 100%. Under the 2 mm/2% criterion, the mean passing rate of PTV was 78.61%±3.90%, and that of OAR was 97.34%±0.96%. Compass is capable of verifying the feasibility of linear accelerator in radiotherapy planning to facilitate the clinical implementation of radiotherapy plans after breast-conserving surgery for breast cancer.