Abstract

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Title:: Quality assurance and quality control for intraoperative photon-based stereotactic body radiotherapy

Author(s):: LI Zhaobin; XIONG Fei; HUANG Guofeng; Department of Radiation Oncology, the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China

Keywords:: ; Keywords: intraoperative radiation therapy; stereotactic body; radiotherapy; quality assurance; quality control

Abstract:: Abstract: Objective From the aspect of the dosimetric characteristics of intraoperative photon-based stereotactic radiotherapy (IORT), to summarize and analyze the monitoring items and methods of quality assurance for IORT and the experiences and considerations in the clinical practice of IORT for ensuring the dosimetric accuracy of IORT, so as to establish an daily quality assurance for IORT. Methods The water phantom, dosimeter and ionization chamber from Carl Zeiss were used to measure the dosimetric data from IORT system. The main monitoring items included dose linearity, stability, homogeneity, the geometric focus of beams, absolute dose calibration and the attenuation in water phantom. Results Intrabeam system produced 50 kV low-energy beams. The dose linearity, homogeneity and short-term stability were within the clinical acceptable range. The dose error was less than 1% within 36 hours. However, the analysis on the dose measurements in 24 months showed that the dose error reached -4.5%. Conclusion The system has a favorable stability and the monitoring items are within clinically required ranges. By measurement, the clinical characteristics of Intarbeam system from Karl Zeiss and the clinically used data are obtained, which provides a method of quality assurance for clinic.