TI-RADS combined with contrast-enhanced ultrasonography in differential diagnosis of benign and malignant thyroid nodules(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第3期
- Page:
- 307-312
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- TI-RADS combined with contrast-enhanced ultrasonography in differential diagnosis of benign and malignant thyroid nodules
- Author(s):
- ZHAO Rong1; YIN Shujun1; WANG Min2
- 1. Department of Ultrasound, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, China; 2. Department of Ultrasound, Chongqing Health Center for Women and Children, Chongqing 401147, China
- Keywords:
- ; thyroid imaging reporting and data system; contrast-enhanced ultrasonography; benign and malignant thyroid nodules; differential diagnosis
- PACS:
- R445.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.03.012
- Abstract:
- Objective To analyze the application value of thyroid imaging reporting and data system (TI-RADS), contrast-enhanced ultrasonography (CEUS), and combined use of them in the differential diagnosis of benign and malignant thyroid nodules. Methods Eighty-seven patients with thyroid nodules treated in Chongqing Traditional Chinese Medicine Hospital from January 2015 to December 2016 were selected as the subjects. All the patients were examined by CEUS, TI-RADS and combined examination. Taken the operational and pathological results as the gold standard, we compared the sensitivity, specificity and accuracy of the 3 examination methods for the differential diagnosis of benign and malignant thyroid nodules. Results There were 117 thyroid nodules, 95 benign nodules and 22 malignant nodules in 87 patients. The maximum diameter of nodules was 0.54-5.19 cm, and the average diameter was (1.50+0.76) cm. The sensitivity, specificity and accuracy of TI-RADS in the diagnosis of benign and malignant thyroid nodules were 45.45% (10/22), 64.21% (61/95) and 60.68% (71/117), respectively. The imaging characteristics of benign and malignant thyroid nodules were significantly different in early enhancement, homogeneous enhancement, and peripheral ring enhancement images (P<0.05). The sensitivity, specificity and accuracy of CEUS in the diagnosis of benign and malignant thyroid nodules were 72.72% (16/22), 92.63% (88/95) and 91.45%(104/117) on early enhancement images; 72.72% (16/22), 74.73% (71/95) and 74.35% (87/117) on homogeneous enhancement images; and 95.45% (21/22) and 31.57% (30/95) and 43.58% (51/117) on peripheral ring enhancement images. The sensitivity, specificity and accuracy of TI-RADS combined with CEUS in the diagnosis of benign and malignant thyroid nodules were 90.90% (20/22), 95.78% (91/95) and 94.87% (111/117). Conclusion TI-RADS combined with CEUS can effectively improve the sensitivity, specificity and accuracy of the differential diagnosis of benign and malignant thyroid nodules.
Last Update: 2018-03-21