Dielectric properties of brain tissues following acute brain injury(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第7期
- Page:
- 899-903
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Dielectric properties of brain tissues following acute brain injury
- Author(s):
- ZHOU Lilong; BAI Zelin; NING Xu; LI Kui; ZHANG Haisheng; XU Lin; WANG Feng; ZHUANG Wei; CHEN Mingsheng
- Teaching and Research Section of Electronic Engineering, Department of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing 400038, China
- Keywords:
- Keywords: acute brain injury microwave tomography electrical property
- PACS:
- R318.6
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.07.017
- Abstract:
-
Abstract: Objective To study the dielectric properties (permittivity and conductivity) of the brain tissues in rabbits with acute brain injury, thereby providing a basis for brain injury detection using microwave tomography. Methods The top of the skull of 10 rabbits in experimental group was hit with a pressure of 0.8 MPa to establish the acute brain injury model. At the craniotomy window at the site of injury, the dielectric properties of the brain tissues were measured using the open-ended coaxial probe in the frequency ranging from 500 MHz to 3 GHz at 30, 45, 60, 75, 90 and 105 min after injury. The 10 rabbits in control group were given the same treatment as that in experimental group except hit on the skull. Results At the same time and frequency, the permittivity and conductivity of brain tissues following acute brain injury were higher than those of normal rabbit brain tissues (P<0.01). At the same time, the permittivity of brain tissues following acute brain injury and normal rabbit brain tissues decreased with increasing frequency, while the conductivity increased with increasing frequency. At the same frequency, the permittivity and conductivity of brain tissues following acute brain injury increased with time, while the permittivity and conductivity of normal rabbit brain tissues remained relatively stable. Conclusion The dielectric properties of brain tissue following acute brain injury changed significantly, indicating that the microwave tomography based on tissue electrical properties is feasible for brain injury detection.
Last Update: 2023-07-15