Abstract

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Title:: Therapeutic effect of transcranial magnetic stimulation under CT localization on poststroke motor dysfunction

Author(s):: XU Yahui; ZHANG Xiaoyun; ZHANG Ran; WANG Peifu; Department of Neurology, Aerospace Central Hospital, Beijing 100049, China

Keywords:: Keywords: stroke CT localization transcranial magnetic stimulation motor dysfunction

Abstract:: Abstract: Objective To observe the treatment efficacy of transcranial magnetic stimulation therapy under CT localization in patients with motor dysfunction after stroke. Methods A total of 150 patients with ischemic stroke were enrolled and divided into observation group (n=75) and control group (n=75) according to the time of admission, and there was no significant difference in the general data between two groups. Patients in observation group were given transcranial magnetic stimulation therapy under CT localization, and those in control group were treated by conventional transcranial magnetic stimulation therapy. The lower extremities muscle strength, upper and lower extremities motor ability, balance and living ability were assessed before and at 8 weeks after treatment. In addition,treatment response rate was also compared between two groups. Results After treatment, the assessment scale scores of lower extremities muscle strength,upper and lower extremity motor ability, balance,living ability in observation group were significantly higher than those in control group (P<0.05). The treatment response rate of observation group was also significantly higher than that of control group (84.00% vs 68.00%, P<0.05). Conclusion Transcranial magnetic stimulation therapy under CT localization is highly effective in patients with poststroke motor dysfunction, and the specific mechanism needs to be further revealed by basic neurobiological research.