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Correlations of mobility of titanium clips in radiotherapy after breast-conserving surgery with breast size and positions of titanium clips(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2022年第5期
Page:
529-534
Research Field:
医学放射物理
Publishing date:

Info

Title:
Correlations of mobility of titanium clips in radiotherapy after breast-conserving surgery with breast size and positions of titanium clips
Author(s):
LUO Jiaojiao1 PENG Haiyan1 LUO Huanli1 ZHOU Xian1 ZENG Xiaohua2 JIN Fu1
1. Department of Radiation Oncology, Cancer Hospital Affiliated to Chongqing University, Chongqing 400030, China 2. Department of Breast Cancer, Cancer Hospital Affiliated to Chongqing University, Chongqing 400030, China
Keywords:
Keywords: breast cancer radiotherapy after breast-conserving surgery cone-beam computed tomography titanium clip
PACS:
R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.05.001
Abstract:
Abstract: Objective To analyze the mobility of titanium clips in patients receiving radiotherapy after breast-conserving surgery, and explore its correlations with the size of the breast and the positions of the titanium clips. Methods Fifteen patients receiving radiotherapy after breast-conserving surgery were randomly enrolled, and each patient underwent CBCT twice a week. The basal surface diameter (D) and the breast height axis (H) of the mammary gland were measured, and the clinical target area was divided into 4 quadrants with the centroid of the tumor bed as the origin. In each quadrant, the mobility (MLR, MAP, MSI) of the titanium clip in the left-right (LR), anterior-posterior (AP) and superior-inferior (SI) directions, and the distances (DSLR, DSAP, DSSI) from the titanium clip to the innermost, foremost and uppermost of the clinical target area were recorded. Results MLR, MAP and MSI were (2.2±3.0), (-1.1±3.6) and (0.8±4.7) mm, respectively. The systematic errors Σ in the left, right, abdomen, back, head and feet directions were 1.7, 2.2, 2.0, 2.4, 2.9 and 3.0 mm, and the random errors σ were 2.4, 4.0, 3.2, 4.0, 4.7 and 4.7 mm and the corresponding margins of target areas were 5.9, 8.3, 7.2, 8.8, 10.5 and 10.9 mm. In the first quadrant, when D×H<99.89 cm2, MAP and D×H were strongly correlated (r=0.805) and MLR and MAP were strongly positively correlated with DSLR, DSAP, and DSSI (r=0.94, 0.94, 0.91 0.87, 0.91, 0.92) and MSI was strongly positively correlated with DSLR and DSAP (r=0.91, 0.94). In the fourth quadrant, when D×H<90.71 cm2, there were strongly negative correlations between MAP and DSLR (r=-0.96), between MSI and DSAP (r=-0.95), while MLR had a strong positive correlation with DSLR (r=0.91). Conclusion The mobility of the titanium clips is anisotropic, with the largest margin in the SI direction, and it is easily affected by the size of the breast and the positions of the titanium clips.

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Last Update: 2022-05-27