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Performance evaluation and analysis of multichannel brain injury detection system based on microwave(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2020年第9期
Page:
1175-1180
Research Field:
医学人工智能
Publishing date:

Info

Title:
Performance evaluation and analysis of multichannel brain injury detection system based on microwave
Author(s):
LIU Yuening ZHUANG Wei ZHANG Haisheng ZHAO Shuanglin CHEN Mingsheng QIN Mingxin
Teaching and Research Section of Electronic Engineering, Department of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing 400038, China
Keywords:
traumatic brain injury microwave test pre-hospital treatment phase difference sensitivity
PACS:
R318.6
DOI:
10.3969/j.issn.1005-202X.2020.09.018
Abstract:
Objective To develop a multichannel detection system based on microwave for the rapid pre-hospital diagnosis of traumatic brain injuries, and to analyze the system sensitivity by physical simulation experiment. Methods The system mainly consists of vector network analyzer, 8-antenna array and multiplexing switch. Different concentrations of physiological saline were used to simulate blood, cerebrospinal fluid, white matter and gray matter which had different electrical conductivities. The S21 phase values of 4 simulated solutions with different volumes (0-10 mL) were measured by a self-made microwave detection system. Each measurement was repeated 4 times. Finally, Matlab and SPSS 20.0 software were used for statistical analysis. Results At scanning frequency of 1-3 GHz, the S21 phase values of 4 simulated solutions measured by each channel of the detection system were decreased with the increase of frequency. At the two characteristic frequency points of 2.20 GHz and 2.85 GHz, the sensitivity of all detection channels to the volume changes of the simulated solutions was statistically significant (P<0.05). At the frequency of 2.20 GHz, the sensitivity of channel 9 was the highest, and the S21 phase had a negative correlation with volume and at the frequency of 2.85 GHz, the sensitivity of channel 4 was the highest, and the S21 phase was positively correlated with volume. The results of Friedman M test showed that there were statistical differences in the S21 phase values of 4 simulated solutions having different electrical conductivities (P<0.05). Conclusion The detection system can be used to distinguish the simulated solutions which have same electrical conductivity and different volumes, and to differentiate various simulated solutions having different electrical conductivities.

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Last Update: 2020-09-25