Abstract

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Title:: Effects of different Geant4 physics lists on boron neutron capture therapy dose calculation

Author(s):: CHEN Zhao; LEI Qin; YANG Peng; WEN Yumei; HE Donglin; WU Zhangwen; GOU Chengjun; Key Laboratory for Radiation Physics and Technology of Ministry of Education/Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610064, China

Keywords:: ; boron neutron capture therapy; boron dose; non-boron dose; dose depth distribution; Geant4; FLUKA

Abstract:: Abstract: Geant4 is an open source Monte Carlo simulation toolkit written in C++, and it provides a variety of physical lists including neutron interactions with matter. Herein several physical lists given by Geant4 are used to calculate the depth distributions of total absorption dose, boron dose and non-Boron dose along the direction of the neutron beam, and the obtained results were compared with FLUKA. The simulation neutron energy is from 0.025 3 eV to 10 MeV. In the studied energy range, the results show that the high-precision neutron physics list (Geant4_HP_T) with S(α,β) thermal model agrees well with FLUKA in the depth distributions of total absorbed dose, boron dose and non-boron dose, which preliminarily verifies that Geant4 can be used in the researches on boron neutron capture therapy (BNCT). For low energy neutrons (<1 MeV), the S(α,β) thermal model has remarkable effects on the depth distribution of BNCT dose, and both QBBC and QGSP_BERT aren’t suitable for the calculation of BNCT dose distributions.