Abstract

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Title:: Advances in research of resting-state fMRI functional connectivity in normal brain aging

Author(s):: LI Qiongge; DONG Chao; ZHAO Haichao; ZHANG Jicong; LIU Tao; School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China

Keywords:: Keywords: brain aging; resting-state; functional magnetic resonance imaging; functional connectivity

Abstract:: Abstract: As a task- free modality of functional magnetic resonance imaging (fMRI) data acquisition and image display, resting- state fMRI is widely used in clinical application. The resting- state functional connectivity based on resting- state fMRI, an important computer-aided analysis method, can be used to detect the fluctuations in brain activity across separate brain regions, which is of great significance for the research of neuroscience related to brain aging. Herein, some basic concepts of functional connectivity were firstly introduced. Then the recent progresses in human brain functional connectivity related to brain aging were summarized. Finally, the existing problems and the development trends of the research of resting state fMRI functional connectivity in normal brain aging were put forward.