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 CT characteristics of hepatic fungal infections in patients with malignant hematological diseases(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2018年第5期
Page:
549-552
Research Field:
医学影像物理
Publishing date:

Info

Title:
 CT characteristics of hepatic fungal infections in patients with malignant hematological diseases
Author(s):
 FENG Qing1 DAI Min2 MA Huayi1 WEI Yiyi1
 1. Department of Radiology, Liuzhou Workers’ Hospital, Liuzhou 545005, China; 2. Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Keywords:
 liver fungal infection computed tomography malignant hematological disease
PACS:
R814.42
DOI:
DOI:10.3969/j.issn.1005-202X.2018.05.010
Abstract:
 Objective To analyze computed tomography (CT) findings of hepatic fungal infections in patients suffering from malignant hematological diseases. Methods The clinical and imaging data of 23 patients with confirmed hepatic fungal infections were retrospectively analyzed. All patients underwent the plain and three-phase enhanced scans of the upper abdomen with a SOMATOM Definition AS 64-slice CT scanner, and the obtained CT findings were analyzed. Results Of all 23 patients, 12 (52.17%) developed liver enlargement. All patients had multiple lesions, and a total of 285 lesions were found in 23 cases. Lesions were round or round-like, with a diameter less than 20 mm. The lesions distributed in scatter or diffusely, without developing in predilection sites. The focal CT findings were able to be divided into 5 types. (1) Lesions appeared simple low density shadows, and the foci were small. Both plain scan and arterial phase showed low density, but portal phase and delayed phase showed equal density. These CT features were observed in 2 cases (8.70%). (2) A total of 10 patients (43.48%) developed annular lesions. Plain scan showed low density shadows in central region. Peripheral enhancement ring was observed in arterial phase, but portal phase and delayed phase showed equal density. (3) Lesion appeared target shape. Plain scan demonstrated low density shadows with relatively clear boundary. Arterial phase revealed a small nodular enhancement in central region, surrounded by low density ring, with an uneven thickness of annular enhancement zone in peripheral region. The low density annular region around the portal and delayed phases had various enhancements, and the peripheral enhancement zone disappears. There were 8 cases (34.78%) of this type. (4) Only 1 case (4.35%) developed lesions which appeared bullous shape. All the 3 phases showed low density in central region, surrounded by enhancement ring. (5) In the last 2 cases, lesions present as irregular mass of multiple nodular fusions, with two or more types of lesions gathering together. Conclusion CT findings of hepatic fungal infection have certain characteristics. Therefore, CT examination has a positive meaning for the diagnosis of hepatic fungal infection, worthy of clinical promotion.

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Last Update: 2018-05-22