Feasibility of Delta4 for plan evaluation based on dose-volume histogram(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第1期
- Page:
- 25-30
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Feasibility of Delta4 for plan evaluation based on dose-volume histogram
- Author(s):
- LIU Lidong1; YANG Zhen2; QIU Xiaoping1; LEI Mingjun2; CAO Ying2; YANG Xiaoyu2; TANG Du2; ZUO Yuhao1
- 1. College of Nuclear Science and Technology, University of South China, Hengyang 421000, China; 2. Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China
- Keywords:
- ; cervical cancer; nasopharyngeal cancer; volumetric modulated arc therapy; Bland-Altman statistical analysis; Delta4; dose-volume histogram; agreement evaluation; feasibility analysis
- PACS:
- R815
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.01.006
- Abstract:
- : Objective To discuss the feasibility of Delta4 for dose-volume histogram (DVH)-based evaluation in plan verification. Methods Taking the three-dimensional (3D) dose reconstruction method based on log files (using Mobius FXTM) as a reference method, we applied Bland-Altman statistical method to analyze the agreement of 3D dose evaluation method based on Delta4 and the reference method in the verification of volumetric modulated arc therapy for cervical cancer and nasopharyngeal cancer (NPC), and to evaluate whether the two methods can be mutually replaced, thus demonstrating the feasibility of Delta4 for the DVH-based evaluation of radiotherapy plan. The indexes used in Bland-Altman agreement analysis included the mean and standard deviation of log files reconstruction dose and Delta4 measured dose, treatment planning system calculated dose and Delta4 planned dose, which were also used to draw the mean-difference scatter plots, respectively. Finally, the agreement of the two methods was determined by the scatter-point distribution interval. Results In the NPC agreement analysis, 99% of measuring points between log files-based reconstructed dose and Delta4 measured dose, and 97% of measuring points between TPS calculated dose and Delta4 planned dose fall within the 95% confidence interval (CI) in mean-difference scatter plots. In the cervical cancer agreement analysis, log files-based reconstructed dose and Delta4 measured dose, TPS calculated dose and Delta4 planned dose had 95% of measuring points within the 95%CI in mean-difference scatter plots, which indicated that the proportion of measurement points outside the 95%CI was within 5%. Conclusion Delta4-based 3D dose evaluation and log files-based 3D dose reconstruction are in a good coincidence and can be mutually replaced. Using Delta4 for DVH-based evaluation is feasible.
Last Update: 2018-01-25