Monte Carlo study of transmission X-ray tubes in kilovoltage radiotherapy(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2025年第7期
- Page:
- 863-871
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Monte Carlo study of transmission X-ray tubes in kilovoltage radiotherapy
- Author(s):
- WU Yikai1; QI Zhongyu1; TAO Li1; ZHANG Hui1; 2; Muhammad Zeeshan1; YE Zirui1; CHANG Yankui1; PEI Xi3; George Xu1
- 1. School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China; 2. Department ofRadiotherapy, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230031, China; 3. Anhui WisdomTechnology Co., Ltd., Hefei 230088, China
- Keywords:
- transmission X-ray tube; kilovoltage X-ray radiotherapy; Monte Carlo; intraoperative radiotherapy; superficialX-ray radiotherapy; dosimetry
- PACS:
- R318；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2025.07.004
- Abstract:
- Abstract: Transmission X-ray tubes are relatively new devices characterized by portability, suitability for miniaturization,and low requirements for shielding, making them ideal radiation sources for kilovoltage X-ray therapy. However, theirapplication in radiotherapy remains underexplored. An electron target model of a transmission X-ray tube is developed usingthe Monte Carlo toolkit TOPAS 3.8.1. The study investigates the effect of tungsten target thickness on X-ray outputefficiency, finding that a tube voltage of 50 kV and a tungsten thickness of 1.4 μm yields the highest emission efficiency.Based on the energy spectrum at this optimal efficiency, polynomial fitting approach is applied to determine thecorresponding aluminum filter thickness for mean energies ranging from 20 keV to 35 keV, achieving a mean fitting error of0.91%. Next, the study simulates dose deposition in a water phantom for spectra with different mean energies and varioussource-to-surface distances, and plots percent-depth-dose curves, relative normalized dose-depth curves, and relativenormalized dose histograms under each treatment condition. Finally, the simulated results are compared with experimentaldata from the intraoperative radiotherapy system Intrabeam and the superficial X-ray therapy unit SRT-100, obtainingaverage relative errors of 3.71% and 4.38%, respectively. These findings provide a theoretical foundation for furtheroptimization of transmission X-ray tubes in kilovoltage radiotherapy.
Last Update: 2025-07-25