Abstract

Info

Title:: Coil design and simulation analysis of magnetic induction hyperthermia in rats

Author(s):: GUO Siwei; LU Mai; Key Lab of Optoelectronic Technology and Intelligent Control of Ministry of Education, Lanzhou Jiaotong University, Lanzhou 730000, China

Keywords:: Keywords: magnetic induction hyperthermia coil coupling field rat model

Abstract:: Abstract: A Helmholtz coil is selected to generate the alternating magnetic field, and the relevant model is established with a rat brain tumor as the research object. Based on the Pennes bioheat transfer equation, the electromagnetic field distribution and temperature field distribution are calculated in COMSOL simulation software, and the factors affecting the outcome of magnetic induction hyperthermia are analyzed. The results show that both magnetic field distribution and temperature field distribution meet the requirements for magnetic induction hyperthermia. The magnetic field distribution in the tumor treatment area is uniform, and the central magnetic induction strength is 12.847 mT. The temperature rise in the tumor area is significant, and the temperature at the tumor center is 46℃ or above, basically reaching the treatment temperature. The therapeutic efficacy of magnetic induction hyperthermia is affected by the number of turns, current, radius and spacing, magnetic field frequency and other parameters. The study provides reference for the clinical application of magnetic induction hyperthermia and the coil design.