Comparison of different registration methods in cone beam CT image guided radiotherapy for breast cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第1期
- Page:
- 7-12
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Comparison of different registration methods in cone beam CT image guided radiotherapy for breast cancer
- Author(s):
- LIU Shuyan1; 2; GAO Xingwang3; LIU Yimei1; ZHOU Yang4; DENG Xiaowu1; CHEN Zhongben5; PENG Yinglin1
- 1. Department of Radiation Oncology, Sun Yat-sen University Cancer Center/State Key Laboratory of Oncology in Southern China/Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China 2. The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510062, China 3. Shenzhen Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, China 4. Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412000, China 5. Xinhua College of Sun Yat-sen University, Guangzhou 510520, China
- Keywords:
- Keywords: breast cancer image-guided radiotherapy cone beam CT positioning error image registration six-dimensional couch
- PACS:
- R318；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.01.002
- Abstract:
- Abstract: Objective To compare the effects of three-dimensional (3D) registration (translation only) and six-dimensional (6D) registration (translation+rotation) on registration accuracy in cone beam CT (CBCT) image guided radiotherapy for breast cancer for providing clinical basis for selecting the optimal image guidance method. Methods The positioning CBCT images before 101 treatments in 18 patients with breast cancer were retrospectively analyzed. The CBCT images and planned CT images were registered by 3D grey-scale image registration and 6D grey-scale image registration, separately. The registration deviation differences in the 3D translation directions of the two registration methods were compared and analyzed and the translation difference (Δ) was calculated. Furthermore, the correlation between rotation angle deviation (R) and translation difference (Δ) was statistically analyzed, and a linear simulation was carried out. Results 3D and 6D registration methods had different translation registration results, in which there were statistical differences in superior-inferior (Y) direction and anterior-posterior (Z) directions ［(-1.47±3.00) mm vs (-0.87±3.27) mm, (-2.91±4.49) mm vs (-3.41±5.38) mm P<0.001］. The rotation angle deviation (R) was correlated with the translation difference (Δ). ΔX and ΔZ had strong linear correlations with Ry (PCC=-0.883, 0.795 P<0.001), and there was a strong linear negative correlation between ΔY and Rx (PCC=-0.722, P<0.001). According to the linear simulation formula, when Rx was greater than 1° and Ry was greater than 2°, there was nearly 1 mm translation difference between the two registration methods in each translation direction. Conclusion The 3D translation registration results significantly differ from 6D translation registration results. The rotation angle of 6D registration affects the translation difference, among which Ry has the greatest impact. It is suggested that when using 6D registration method, 6D couch should be used to correct 6D deviations in order to reduce the effects of translation difference.
Last Update: 2023-01-07