Analysis of setup errors in patients with esophageal or lung cancer using CBCT(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第10期
- Page:
- 1189-1193
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Analysis of setup errors in patients with esophageal or lung cancer using CBCT
- Author(s):
- XIAO Liangjie1; 2; FANG Yongwen1; WANG Yuliu1; LIN Xiaosheng1; XU Senkui1; 2; YAO Wenyan1; ZHAO Lei1; FANG Jianlan1
- 1. Department of Radiotherapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, China 2. Guangdong Institute of Esophageal Cancer, Guangzhou 510060, China
- Keywords:
- Keywords: cone-beam CT esophageal cancer lung cancer six-dimensional couch setup error
- PACS:
- R815.6；R735.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.10.001
- Abstract:
- Abstract: Objective To analyze the 6-dimensional setup errors of esophageal cancer and lung cancer with the use of cone-beam CT (CBCT), and to discuss the necessity and clinical significance of 6-dimensional couch for translational and rotational errors correction in esophageal cancer. Methods Patients with thoracic tumors treated with radiotherapy at Sun Yat-sen University Cancer Center from October 2019 to December 2021 were enrolled, with 85 cases each in esophageal cancer group and lung cancer group. The first 3 CBCT scans of all patients were collected for obtaining the 6-dimensional setup errors, including superior-inferior (SI), left-right (LR), anterior-posterior (AP) directional setup errors, and rotational setup errors around Z-axis (RTN), X-axis (PITCH), Y-axis (ROLL). The absolute values of the raw data were analyzed by Kolmogorov-Smirnov Z nonparametric rank sum test. Results The absolute values of SI, LR, and AP setup errors were 0.30 (0.10, 0.50), 0.10 (0.10, 0.30), 0.10 (0.10, 0.20) cm in esophageal cancer group, and 0.20 (0.10, 0.40), 0.20 (0.10, 0.30), 0.10 (0.10, 0.30) cm in lung cancer group. The RTN, PITCH, and ROLL setup errors were 0.50° (0.30°, 0.90°), 0.90° (0.40°, 1.60°), 0.90° (0.40°, 1.40°) in esophageal cancer group, and 0.40° (0.10°, 0.70°), 0.70° (0.20°, 1.30°), 0.50° (0.10°, 1.00°) in lung cancer group. There were statistically significant differences between esophageal cancer group and lung cancer group in SI, RTN, PITCH and ROLL setup errors (P<0.05), but not in LR and AP setup errors (P>0.05). Conclusion Guided by CBCT, 6-dimensional registration technique with 6-dimensional couch can reduce the setup errors during radiotherapy for thoracic tumors, especially for long target areas such as esophageal cancer, and has obvious advantages in correcting the rotational setup errors.
Last Update: 2022-10-27