Abstract

Info

Author(s):: TANG Moxiong; LI Xiaolong; School of Electronic Information, Jiangsu University of Science and Technology, Zhenjiang 212003, China

Keywords:: Keywords: epileptic EEG signal bio-signal preamplifier biphasic stimulation pulse generator electromagnetic coupling

Abstract:: Abstract: A wireless closed-loop vagus nerve stimulator and its system which includes a head-mounted scalp EEG recorder, a vagus nerve stimulator, an electromagnetic coupling energy transmitter and a control App are proposed for the treatment of drug-refractory epilepsy. A bio-signal preamplifier that can separate local field potential and action potential, a vagus nerve stimulator that can generate biphasic stimulation pulses with adjustable parameters, an electromagnetic coupling energy transmitter and a control App are designed. The coastline parameter algorithm is used to detect the generation of epileptic signals. The test results show that the amplification gains of the bio-signal preamplifier for local field potential and action potential are 40 and 60 dB, respectively. The vagus nerve stimulator can generate the corresponding biphasic stimulation pulses after it receives stimulation parameters from the control App. When the transmitter power is 30 dBm and the distance between the transmitter coil and the receiver coil is 2 cm, the maximum electromagnetic coupling energy transmission efficiency reaches 15.4%. The detection accuracy of the coastline parameter algorithm is 88%.