Modeling and analysis of electrical signal transduction mechanism in electroacupuncture-based electrochemotherapy of intramuscular hemangioma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第9期
- Page:
- 1145-1150
- Research Field:
- 医学信号处理与医学仪器
- Publishing date:
Info
- Title:
- Modeling and analysis of electrical signal transduction mechanism in electroacupuncture-based electrochemotherapy of intramuscular hemangioma
- Author(s):
- ZHANG Shuang1; 2; 3; 4; 5; XU Jing1; 4; 5; YU Yuanyu1; 4; 5; WANG Jiujiang1; 4; 5; KUANG Jiangming1; 4; 5; YANG Jining1; 4; 5; ZHANG Tao2; 3
- 1. School of Artificial Intelligence, Neijiang Normal University, Neijiang 641100, China 2. School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China 3. High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu 611731, China 4. Smart Medical Engineering Applications Laboratory, Neijiang Normal University, Neijiang 641100, China 5. NJNM-OMNISKY Smart Medical Engineering Applications Joint Laboratory, Neijiang Normal University, Neijiang 641100, China
- Keywords:
- Keywords: electroacupuncture electrochemotherapyfinite element model intramuscular hemangioma electrical signal transduction mechanism
- PACS:
- R318；Q42
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.09.015
- Abstract:
- Abstract: Objective In the electrochemical therapy based on electroacupuncture, the electrolysis and electroosmosis of tumor cells are realized by injecting direct electrical signal into electroacupuncture to generate current diffusion, so as to achieve the targeted and precision treatment of cancer. The signal transmission of electroacupuncture signal in arm muscle is analyzed in the study for providing theoretical basis for precision treatment. Methods By combining human anatomy and histological structure, the numerical simulation finite element model of electroacupuncture-based electrochemotherapy was established in COMSOL Multiphysics 5.5 software, with the round table, cylinder and ellipsoid as geometric entities.The electrical signal transduction mechanism in the arm was analyzed by injecting the direct electrical signal of ±20 mA with carrier signal of 100 kHz in the frequency domain environment. Results The distributions of inductive potential and current density were mainly concentrated around the head of bare electroacupuncture, and the potential attenuation was about 11 dB/cm. When the distance became larger, the current signal injected through electroacupuncture could hardly be detected. Conclusion In the electrochemotherapy for precision treatment of tumor, the farther the conduction distance is, the greater the signal attenuation is. When the distance is large enough, the current signal injected through electroacupuncture can hardly be detected at the detection end, which shows clearly that electroacupuncture treatment will hardly affect the equipment located at a certain distance from it (the distance depends on the electroacupuncture size and the injection current).
Last Update: 2022-09-27