Dosimetric comparison among 3 kinds of brachytherapy techniques in cervical cancer(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第10期
- Page:
- 1199-1203
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Dosimetric comparison among 3 kinds of brachytherapy techniques in cervical cancer
- Author(s):
- CHENG Jianqiang; AN Yongwei; TAO Na; NIU Ruijun; WEI Xiyi; ZHANG Chunlin; GAO Liying; WEI Shihong
- Department of Radiation Oncology, Gansu Provincial Cancer Hospital, Lanzhou 730050, China
- Keywords:
- Keywords: cervical cancer brachytherapy 3D printing interstitial treatment
- PACS:
- R737.33；R816.91
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.10.003
- Abstract:
- Abstract: Objective To analyze the differences in doses to target areas and organs-at-risk during brachytherapy in different modes. Methods According to the different modes of the applicator, 72 patients with cervical cancer were divided into 3 groups, namely conventional three-dimensional intracavitary brachytherapy (ICBT) group, interstitial brachytherapy (ISBT) group and 3D printing interstitial brachytherapy (3DP-ISBT) group. The doses to organs-at-risk in different groups were analyzed. Results The average number of interstitial needles in 3DP-ISBT group was more than that of ISBT group (6 vs 4, P<0.001). The comparison between any 2 groups showed that there was no significant difference in D90 and target volume of HR-CTV (P>0.05). The D0.1 cc, D1 cc and D2 cc of the bladder in ISBT group and 3DP-ISBT group were significantly lower than those in ICBT group (P<0.01), but the differences between ISBT group and 3DP-ISBT group were trivial (P=0.993). No significant difference was found in the D0.1 cc, D1 cc and D2 cc of the rectum among 3 groups. The D0.1 cc, D1 cc and D2 cc of the small intestine in ISBT group and 3DP-ISBT group were significantly lower than those of ICBT group (P<0.01), and the D0.1 cc, D1 cc and D2 cc of the small intestine in 3DP-ISBT group were significantly lower than those of ISBT group (P<0.01). Conclusion By analyzing the exposure doses to organs-at-risk in 3 brachytherapy modes, ISBT is advantageous over ICBT in sparing of bladder and small intestine. Among them, 3DP-ISBT has the optimal performance in the protection of the bladder and small intestine, but it shows no advantages in rectal sparing.
Last Update: 2022-10-27