Abstract

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Title:: Delivered dose verification for stereotactic body radiotherapy in non-small cell lung cancer using kilovoltage cone-beam computed tomography image

Author(s):: DUAN Yuxin1; DENG Zhenxiang2; LIU Xi3; ZHU Zongda2; 1. Department of Radiation Oncology, Southern Theater Command Air Force Hospital, Guangzhou 510600, China 2. Department of Radiation Oncology,Xiangan Hospital of Xiamen University, Xiamen 361101, China 3. School of Medical Information and Engineering, Guangdong Pharmaceutical University, Guangzhou 510006, China

Keywords:: Keywords: non-small?ell?ung?ancer stereotactic body radiotherapy cone-beam computed tomography dose verification

Abstract:: Abstract: Objective To verify the delivered dose of stereotactic body radiotherapy (SBRT) in non-small cell lung cancer (NSCLC) using kilovoltage cone-beam computed tomography (kV-CBCT) image. Methods A total of 100 CBCT images were collected from 20 patients receiving SBRT for NSCLC. Delivered fractionated dose distributions were recalculated on CBCT images using deformable registration and non-deformable registration, separately. The planned and delivered dose distributions were compared using dose-volume histograms. Results The relative differences in the average target coverage (V100%) of internal target volume were small. The conformity index and gradient index showed a good agreement among the plans. For the organs-at-risk, significant differences between the planned dose and delivered dose were found in only one patient (P<0.05). Conclusion CBCT images can be used to verify the delivered dose of SBRT in NSCLC and provide relevant 3D executive dose information.