Role of CT in assessing severe acute pancreatitis and liver damage(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第3期
- Page:
- 311-316
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Role of CT in assessing severe acute pancreatitis and liver damage
- Author(s):
- LI Huangen; HUANG Minglian; HUANG Youpei; ZHENG Wenbo; CHEN Weiwen
- Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China
- Keywords:
- Keywords: computed tomography acute severe pancreatitis infection liver damage procalcitonin C-reactive protein
- PACS:
- R657.51
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.03.009
- Abstract:
- Abstract: Objective To analyze the clinical application value of computed tomography (CT) in the assessment of severe acute pancreatitis (SAP) and liver damage. Methods Eighty-four SAP patients were classified into mild group (n=36) and severe group (n=48) according to their condition, and the severe group accepted CT-guided percutaneous catheter drainage (PCD). The CT imaging characteristics were analyzed, and the correlations of serum C-reactive protein (CRP) and procalcitonin (PCT) levels to liver CT value (HU) in two groups before and after treatment were discussed. Results CT imaging findings showed that the detection rates of pancreatic flaky necrosis, air bubbles, multi-regional pancreatic juice retention, obscured fat layer and volume increase in severe group were significantly higher than those in mild group (P<0.05). CT images showed that pancreatic necrosis area in patients with pancreatitis caused by hyperlipidemia ranged from 30% to 50%, with surrounding fluid and exudation, swelling of the tail, and flaky necrosis, and that the necrosis area in patients with acute pancreatitis was larger than 50%, with bilateral pleural effusion, and peripheral abscess formation. Serum CRP and PCT levels of severe group were significantly higher than those of mild group (P<0.05). Before treatment, the liver HU of severe group was significantly lower than that of mild group (P<0.05), but the difference between two groups in liver HU after treatment was trivial (P>0.05). Before treatment, the liver HU of severe group was negatively correlated with PCT and CRP levels (r=-0.643, r=-0.568 P<0.05) after treatment, there was no significant correlation between liver HU and PCT or CRP level (r=-0.084, r=-0.056 P>0.05). Compared with mild group, severe group had obviously longer treatment duration, lower cure rate and higher mortality rate (all P<0.05). Conclusion CT can be used to effectively assess the severity of SAP co-infected patients, and to observe the changes in liver density, thereby assessing liver damage in SAP patients.
Last Update: 2022-03-28