Effects of theta burst stimulation on upper limb motor function and activities of daily living in patients after stroke: a Meta analysis(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第3期
- Page:
- 341-348
- Research Field:
- 医学信号处理与医学仪器
- Publishing date:
Info
- Title:
- Effects of theta burst stimulation on upper limb motor function and activities of daily living in patients after stroke: a Meta analysis
- Author(s):
- XIA Yuan1; LU Yue1; LI Ailing2; WANG Zhenyu1; PAN Xinyong1; LI Yongjie3
- 1. School of Health Sciences, Wuhan Sports University, Wuhan 430079, China 2. Department of Neurology, Tianshui 407 Hospital of Gansu, Tianshui 741000, China 3. Department of Rehabilitation Medicine, Guizhou Provincial Orthopedics Hospital, Guiyang 550002, China
- Keywords:
- Keywords: theta burst stimulation stroke upper limb motor function
- PACS:
- R312；R741.05
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.03.014
- Abstract:
- Abstract: Objective To systematically evaluate the effects of theta burst stimulation (TBS) on the upper limb motor function and activities of daily living in patients after stroke. Methods The randomized controlled trials of TBS in the treatment of stroke patients were retrieved from ProQuest, Scopus, PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, China Biomedicine (CBM) and Weipu databases, and the retrieval time was from the establishment of the database to April 2021. Two reviewers used the Cochrane manual to evaluate the risk and quality of the included literatures, and a statistical analysis by RevMan5.3 was carried out after data extraction. Results Fourteen literatures were finally included in the study, with a total of 329 subjects. Meta-analysis results showed that compared with conventional rehabilitation group, TBS group reduced the National Institutes of Health Stroke Scale (NIHSS) score ［WMD=-4.11, 95%CI (-6.99, -1.23), P=0.005］, improved the modified Barthel index (MBI) score ［WMD=9.54, 95%CI (3.81, 15.27), P=0.001］ and improved the action research arm test (ARAT) score ［WMD=8.83, 95%CI (3.26, 14.40), P=0.002］, and the differences were statistically significant (P<0.05). In addition, TBS group was better than conventional rehabilitation group in improving the upper extremity Fugl-Meyer assessment (UE-FMA) score ［WMD=7.24, 95%CI (2.18, 12.31), P=0.005］, and the subgroup results revealed that intermittent TBS might be more effective than continuous TBS in improving UE-FMA score (P=0.04). Conclusion Based on current evidence, TBS can effectively improve upper limb motor function and activities of daily living in stroke patients, but the above conclusion still needs to be further confirmed by more high-quality researches.
Last Update: 2022-03-28