Diagnostic value of dynamic CEUS-TIC quantitative analysis in recurrent small hepatocellular carcinoma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第4期
- Page:
- 459-463
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic value of dynamic CEUS-TIC quantitative analysis in recurrent small hepatocellular carcinoma
- Author(s):
- JIN Lijia; TANG Yizhi; CHEN Peng; LIU Jikui
- Center of Ultrasound, 363 Hospital/Chengdu 363 Hospital Affiliated to Southwest Medical University, Chengdu 610041, China
- Keywords:
- Keywords: hepatocellular carcinoma dynamic contrast-enhanced ultrasound time-intensity curve diagnostic value
- PACS:
- R735.7
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.04.012
- Abstract:
- Abstract: Objective To explore the value of dynamic contrast-enhanced ultrasound time-intensity curve (CEUS-TIC) quantitative analysis to diagnose recurrent small hepatocellular carcinoma. Methods A total of 197 lesions in 159 patients with recurrent small hepatocellular carcinoma after hepatectomy were selected and confirmed by pathology. All patients underwent CEUS examination. The pathological diagnostic results were taken as the standards to analyze the differences in CEUS parameters and perfusion patterns in each time phase between malignant group and benign group. Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of dynamic CEUS-TIC quantitative parameters in recurrent small hepatocellular carcinoma, and the sensitivity, specificity and area under the curve (AUC) were calculated. Results CEUS showed that there were 84 benign lesions and 113 malignant lesions. The accuracy rate of CEUS in the diagnosis of malignant lesions was 85.61% (113/132). The initial time of enhancement, time to peak, initial time of iso-enhancement and initial time of hypo-enhancement in malignant group were significantly shorter than those in benign group (t=4.929, 11.231, 5.400, 9.652 P<0.05). There was no statistically significant difference in the arterial phase distribution between two groups (Z=0.700, P>0.05), and the proportions of hyper- or iso-enhancement in portal phase and hypo-enhancement in delayed phase in malignant group were significantly higher than those in benign group (Z=2.280, 2.160 P<0.05). The specificity and AUC of the combined diagnosis of initial time of enhancement, time to peak, initial time of iso-enhancement and initial time of hypo-enhancement were 92.30% and 0.942, higher than those of single diagnosis of each parameter which were 66.20%, 75.40%, 43.10%, 84.60%, and 0.767, 0.808, 0.710, 0.838, respectively. Conclusion Dynamic CEUS-TIC quantitative analysis has good diagnostic value in recurrent small hepatocellular carcinoma, and it is a simple and feasible method for diagnosing recurrent small hepatocellular carcinoma.
Last Update: 2022-04-27