Diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan for solitary pulmonary nodules(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第6期
- Page:
- 713-716
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan for solitary pulmonary nodules
- Author(s):
- LIU Xiaofeng1; HUANG Shubin2; HU Lei1
- 1. Department of Medical Imaging, Chizhou Peoples Hospital, Chizhou 247000, China 2. Department of Pathology, Chizhou Peoples Hospital, Chizhou 247000, China
- Keywords:
- Keywords: solitary pulmonary nodule computed tomography dynamic contrast-enhanced scan time-density curve characteristic parameter
- PACS:
- R816.4
- DOI:
- DOI:10.3969/j.issn.1005-202X.2021.06.010
- Abstract:
- Abstract: Objective To analyze the diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced computed tomography (CT) scan for solitary pulmonary nodules. Methods The clinical data of 95 patients with solitary pulmonary nodules were retrospectively analyzed. All patients underwent dynamic contrast-enhanced CT scan and pathological biopsy. According to the pathological results, the specificity, sensitivity and accuracy of dynamic contrast-enhanced CT scan in the diagnosis of solitary pulmonary nodules were analyzed. The time-density curves and characteristic parameters of different types of solitary pulmonary nodules were compared and analyzed. Results There were 67 malignant nodules, 14 benign nodules and 14 inflammatory nodules in 95 patients with solitary pulmonary nodules. The specificity, sensitivity and accuracy of dynamic contrast-enhanced CT in diagnosing solitary pulmonary nodules were 83.33%, 95.38% and 91.58%, respectively. The CT values of patients with malignant nodules and inflammatory nodules at each time point in dynamic contrast-enhanced CT scan were higher than those in benign nodules group (P<0.05). At 300 s and 480 s of dynamic contrast-enhanced CT scan, the CT value of inflammatory nodules group was significantly lower than that of malignant nodules group (P<0.05). The peak?eight (PH) and the ratio between PH of solitary pulmonary nodules and aortic PH (SPH/PPH) of malignant nodules group and inflammatory nodules group were significantly higher than those of benign nodules group (P<0.05). Conclusion The time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan can provide certain diagnostic basis for benign and malignant solitary pulmonary nodules.
Last Update: 2021-06-29