Construction of pencil beam model in DeepPlan based on clinical proton accelerator(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第3期
- Page:
- 287-294
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Construction of pencil beam model in DeepPlan based on clinical proton accelerator
- Author(s):
- ZHANG Zengpeng1; 2; TAO Yin1; 2; LIU Hongdong3; CHEN Zhi1; 2; XU Xie1; 2; 4; PEI Xi1; 2; 4
- 1. School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China 2. Institute of Nuclear Medical Physics, University of Science and Technology of China, Hefei 230025, China 3. Department of radiotherapy, Sun Yat-sen University Cancer Center, Guangzhou 510060, China 4. Anhui Wisedom Technology Co.Ltd, Hefei 230088, China
- Keywords:
- Keywords: proton accelerator proton dose calculation DeepPlan pencil beam model treatment planning system
- PACS:
- R318；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2021.03.004
- Abstract:
- Abstract: Objective Based on the clinical experimental data of University of Florida Health Proton Therapy Institute (UFHPTI) proton accelerator in the pencil beam scanning mode, a corresponding model is constructed in DeepPlan to verify the accuracy of model construction, and the model is preliminarily applied to the dose calculation of prostate cancer. Methods The pencil beam calculation model of UFHPTI proton accelerator was established in DeepPlan proton module. The results of dose calculation were compared with clinical experimental data, including 30 groups of integrated depth dose, 30 groups of proton beam spot divergence in the air, and a set of longitudinal spread out Bragg peak and transverse dose distribution under multi-energy and multi-point irradiation, so as to verify the accuracy of model construction. Finally, guided by the clinical radiotherapy plans of 2 cases of prostatic cancer in UFHPTI, the calculation results of DeepPlan and those of commercial radiotherapy planning system RayStation were analyzed by VeriSoft software of PTW for gamma analysis. Results The average relative error of 30 groups of integrated depth dose between clinical experimental data of UFHPTI accelerator and those calculated by DeepPlan proton module was 0.01%, with the maximum relative error of 0.23%. The average relative error of 30 groups of proton beam spot divergence in the air between the calculated results of DeepPlan proton module and clinical experimental data was 0.15%, with the maximum relative error of 1.14%. Under multi-energy and multi-point irradiation, the average relative error of spread out Bragg peak calculated by DeepPlan proton module and clinical experimental data was 1.07%, with the maximum relative error of 3.91% and the average relative error of transverse dose distribution calculated by DeepPlan proton module and clinical experimental data was 1.92%, with the maximum relative error of 4.09%. For the radiotherapy plans of 2 cases of prostate cancer, the three-dimensional doses calculated by DeepPlan proton module and RayStation reached a gamma passing rate of more than 95% for each subfield under the criterion of 3mm/3%. The gamma passing rates of two subfields (270° and 90°) in case 1 were 96.4% and 97.5%, and those of two subfields (270° and 90°) in case 2 were 99.3% and 98.9%. Conclusion A pencil beam model matching with UFHPTI proton accelerator is constructed in DeepPlan, and the constructed model can be preliminarily applied to the dose calculation of prostate cancer.
Last Update: 2021-03-30