Diagnostic value of diffusion-weighted magnetic resonance imaging in malignant and benign hepatic focal lesions(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第7期
- Page:
- 894-897
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic value of diffusion-weighted magnetic resonance imaging in malignant and benign hepatic focal lesions
- Author(s):
- CHEN Fei1; TANG Shu2
- 1. Department of Radiology, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. Department of Medical Oncology, the South Branch of Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China
- Keywords:
- Keywords: hepatic focal lesions magnetic resonance diffusion-weighted imaging apparent diffusion coefficient
- PACS:
- R735.7
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.07.018
- Abstract:
- Abstract: Objective To investigate the value of diffusion-weighted magnetic resonance imaging (DWI) in the differential diagnosis of malignant and benign hepatic focal lesions. Methods All the enrolled 83 patients with hepatic focal lesions were examined by conventional MRI and DWI. After selecting the regions of interest in DWI, the apparent diffusion coefficients (ADC value) under different diffusion sensitivity coefficients (b value) were determined, and the DWI signal characteristics of patients with hepatic focal lesions were analyzed. The ADC values of patients with benign and malignant lesions were compared under different b values. The results of the differential diagnosis by conventional MRI and DWI were then compared with pathological results for evaluating the diagnostic efficiency. Results There were 57 cases of malignant lesions, including 22 cases of liver metastasis and 35 cases of primary liver cancer, and 26 of benign lesions, including 12 cases of liver cyst and 14 cases of liver hemangioma. On DWI, primary liver cancer was manifested as high or mixed signals and liver metastasis and liver hemangioma had high signals and the signal of liver cyst was hypointense. Under high, middle, low b values, the ADC values of malignant hepatic focal lesions were lower than those of benign hepatic focal lesions (P<0.05). The specificity and accuracy of DWI in the diagnosis of malignant hepatic focal lesions were higher than those of conventional MRI (96.15% vs 69.23%, 90.36% vs 72.29% P<0.05), and the misdiagnosis rate was lower than that of conventional MRI (3.85% vs 30.77%, P<0.05). There was no significant difference in the sensitivity and the rate of missed diagnosis between two methods in the diagnosis of malignant hepatic focal lesions (87.72% vs 73.68%, 12.28% vs 26.32% P>0.05). Conclusion In the differential diagnosis of malignant and benign hepatic focal lesions by MRI, DWI can effectively improve the diagnostic specificity and accuracy for malignant hepatic focal lesions by comparing the DWI image signal characteristics and ADC values of patients with malignant and benign hepatic focal lesions.
Last Update: 2020-07-28