Abstract

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Title:: Dosimetric comparison between automatic planning and manual planning in volumetric modulated arc therapy of cervical cancer

Author(s):: WU Jianchi1; DENG Ting1; ZHAO Ying2; 1. Department of Gynaecology, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. Outpatient Department, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou 545001, China

Keywords:: Keywords: cervical cancer automatic planning manual planning volumetric modulated arc therapy radiation dose

Abstract:: Abstract: Objective To observe and compare the dose parameters between automatic planning and manual planning in volumetric modulated arc therapy (VMAT) for patients with cervical cancer after surgery, and to study the feasibility of automatic planning in postoperative radiotherapy of cervical cancer. Methods Thirty patients with cervical cancer who received radiotherapy in Chenzhou No.1 Peoples Hospital from November 2018 to November 2019 were enrolled for clinical analysis and exploration. Pinnacle treatment planning system was used for manual and automatic VMAT planning. The D95, Dmean, homogeneity index, conformity index of target areas and the dose parameters of organs-at-risk were compared between two plans. Results There were significant differences in the Dmean, homogeneity index and conformity index of target areas between manual planning and automatic planning (P<0.05), but not in D95 (P>0.05). Moreover, there were statistical differences in the dose-volume parameters of bladder, bone, small intestine, rectum, right femoral head and left femoral head between manual planning and automatic planning (P<0.05). Conclusion Compared with manual VMAT planning, automatic VMAT planning has higher planning quality and can improve the rationality of dose distribution. The VMAT plan automatically planned by Pinnacle treatment planning system which has higher clinical feasibility can be applied to the postoperative radiotherapy of cervical cancer.