Application value of conventional 3 sections and special cross section in the ultrasonic screening of cleft lip and palate in fetuses(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第3期
- Page:
- 322-325
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application value of conventional 3 sections and special cross section in the ultrasonic screening of cleft lip and palate in fetuses
- Author(s):
- LU Zhanhui; CHEN Ting; DENG Yiye; ZHENG Dacong
- Fetal Ultrasound Group, Foshan Women and Children Hospital, Foshan 528000, China
- Keywords:
- Keywords: fetus; cleft lip and palate; ultrasound examination; conventional 3 sections; special cross section
- PACS:
- R788；R445.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2020.03.013
- Abstract:
- Abstract: Objective To investigate the application value of conventional 3 sections combined with special cross section in the ultrasound screening of fetal cleft lip and palate. Methods A total of 6 000 pregnant women in Foshan Women and Children Hospital were enrolled in the study. The lips and palates of 2 556 fetuses were examined by single section (control group), while the lips and palates of 3 444 fetuses were examined by conventional 3 sections and special cross section (observation group). With the facial examination of neonates as the golden standard, the sensitivity, specificity, accuracy, positive predictive value, negative predictive value and the rate of missed diagnosis were compared between control group and observation group. Results There were 47 cases (0.78%) with cleft lip and palate, with 20 cases (0.78%) in control group and 27 cases (0.78%) in observation group. There was no significant difference in the rate of cleft lip and palate between two groups (P>0.05). The sensitivity, specificity, accuracy, the rate of missed diagnosis, positive predictive value, negative predictive value and Kappa value in control group were 60.00%, 99.88%, 99.57%, 40.00%, 80.00%, 99.69% and 0.68, respectively, while those in observation group were 92.59%, 100.0%, 99.94%, 7.41%, 100.00%, 99.94% and 0.96, respectively. The sensitivity, accuracy and negative predictive value in observation group were significantly higher than those in the control group (P<0.05). Conclusion The conventional 3 sections combined with special cross section in ultrasonic examination can effectively improve the screening accuracy of fetal cleft lip and palate, with a higher application value.
Last Update: 2020-04-02