Diagnostic value of Gd-EOB-DTPA enhanced MRI and DWI in residual or recurrent lesions
after TACE for hepatocellular carcinoma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2020年第5期
- Page:
- 561-567
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic value of Gd-EOB-DTPA enhanced MRI and DWI in residual or recurrent lesions
after TACE for hepatocellular carcinoma
- Author(s):
- LIU Haifeng; XU Yongsheng; LIU Zhao; LU Xingru; LEI Junqiang
- Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China
- Keywords:
- Gd-EOB-DTPA diffusion weighted imaging hepatocellular carcinoma transcatheter arterial chemoembolization
- PACS:
- R735.7；R816
- DOI:
- 10.3969/j.issn.1005-202X.2020.05.006
- Abstract:
- Objective To investigate the value of Gd-EOB-DTPA enhanced magnetic resonance imaging (MRI) and diffusion
weighted imaging (DWI) in the diagnosis of residual or recurrent lesions after transarterial chemoembolization (TACE) for
hepatocellular carcinoma (HCC). Methods Aprospective and consecutive study was performed on 96 patients with 129 HCC lesions
who had undergone TACE. The follow-up results by CT and/or MRI and surgery pathology were taken as
the diagnostic gold standard, and the diagnostic accuracy of Gd-EOB-DTPA enhanced MRI and DWI in detecting residual or
recurrent lesions at 1-2 months after TACE for HCC was investigated. Meanwhile, receiver operating characteristics (ROC) curve
was used to evaluate the value of apparent diffusion coefficient (ADC) in the differential diagnosis of residual or recurrent lesions.
Moreover, the diagnostic value of imaging signs in residual or recurrent lesions after TACE was explored by Chi-square test. The
discussed imaging signs included T1WI signal, T2WI signal, morphology, capsule, DWI signal, arterial-phase enhancement
performance and liver-specific phase signal. Results The evaluation by gold standard confirmed that there were 29 residual lesions,
18 hepatic recurrent lesions and 82 necrotic lesions after TACE. The residual or recurrent lesions after TACE were characterized
with hypointense on T1WI, hyperintense on T2WI and hyperintense on DWI. The residual or recurrent lesions with enhancement
in arterial phase accounted for 89.36% (42/47) and those without hypointense of contrast agent uptake in hepatocellular phase
accounted for 91.49% (43/47). The sensitivity and specificity of Gd-EOB-DTPA enhanced MRI in the diagnosis of residual or
recurrent lesions after TACE were 93.62% and 96.34%, respectively, and those of DWI were 91.49% and 95.12%, respectively. The sensitivity and specificity of the combination reached 95.74% and 100.00%. No capsule, hyperintense on DWI and the
enhancement of arterial-phase signal were important independent factors in diagnosing residual or recurrent lesions after TACE
(P<0.05). Conclusion Gd-EOB-DTPAenhanced MRI combined with DWI has excellent diagnostic value in residual or recurrent
lesions after TACE in HCC and can be used in the clinical follow-up after TACE.
Last Update: 2020-06-03