Comparison of CT findings of peripheral lung cancer with spiculations and inflammatory nodules with spiculations(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第11期
- Page:
- 1276-1280
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Comparison of CT findings of peripheral lung cancer with spiculations and inflammatory nodules with spiculations
- Author(s):
- GUO Yuefei; DUAN Ya’ni; DONG Yunxu; ZHU Yanqiu; CHEN Xiuzhen; QIN Jie
- Department of Radiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China
- Keywords:
- ; Keywords: lung cancer; lung inflammatory nodule; spiculation; X-ray computed tomography
- PACS:
- R445.3；R734.2
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.11.007
- Abstract:
- Abstract: Objective To compare the CT images of lung cancer with spiculations and inflammatory nodules with spiculations. Methods A total of 73 cases of pathologically confirmed solitary pulmonary nodules with spiculations and a diameter ≤3 cm were selected, including 42 cases of lung cancer and 31 of inflammatory nodules. The CT features of all these cases, including the size, density, enhancement, lobulation, cavity of nodules, and the lengths, diameters, number and distribution of spiculations, were compared between lung cancer and inflammatory nodules. Results Lung cancer with spiculations were significantly larger than the inflammatory nodules with spiculations, with statistical differences ［(1.93±0.65) cm vs (1.46±0.56) cm, t=3.24, P<0.05］. Lobulation was more common in lung cancer group than in inflammatory nodules group (50.00% vs 25.81%, [χ2]=4.36, P<0.05), while the incidence of cavity was similar in inflammatory nodules group and in lung cancer group (9.68% vs 14.29%, [χ2]=0.35, P>0.05). No statistical differences were found in CT density and enhancement between lung cancer group and inflammatory nodules group (44.94±2.88 vs 39.83±3.26, P>0.05; 29.07±2.80 vs 27.70±4.46, P>0.05). The number of spiculations in lung cancer was more than that in inflammatory nodules, with statistical significance (5.57±3.33 vs 3.68±2.40, t=2.69, P<0.05), but the diameter of spiculations in lung cancer was close to that in inflammatory nodules (1.62±0.80 vs 1.54±0.63, t=0.42, P>0.05). The spiculations of lung cancer were distributed mainly in periphery in 28.57% (12/42) patients, pleura in 54.29% (27/42) patients and hilum of the lung in 7.14% (3/42) patients, and the spiculations of inflammatory nodules were distributed mainly in periphery in 29.03% (9/31) patients, pleura in 58.07% (18/31) patients and hilum of the lung in 12.90% (4/31) patients. There was no statistical differences in the spiculation distribution between lung cancer group and inflammatory nodules group ([χ2]=0.73, P>0.05). Conclusion The size, lobulation of nodules and number of spiculations are helpful in distinguishing lung cancer and inflammatory nodules, while the diameter and distribution of spiculation are of no help. Large lobulated nodules with more spiculations indicate that the nodules are more likely to be lung cancer.
Last Update: 2018-11-22