Characteristics of medical proton irradiation beams based on ultra-intense pulse laser(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第6期
- Page:
- 621-625
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Characteristics of medical proton irradiation beams based on ultra-intense pulse laser
- Author(s):
- MU Hongchen1; WANG Guangchang2; LIANG Dong2; CHEN Xu2; ZHANG Jianwei2; ZHENG Zhijian3
- 1. College of Physics and Electronic Engineering, Harbin Normal University, Harbin 150080, China; 2. Teaching and Research Section of Physics, Chengdu Medical College, Chengdu 610500, China; 3. Research Center of Laser Fusion, CAEP, P.O. Box 919-986, Mianyang 621900, China
- Keywords:
- ; Keywords: ultra-intense pulse laser; medical proton irradiation beam; spatial distribution; beam density
- PACS:
- R312；TN247
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.06.001
- Abstract:
- Abstract: Objective To explore the medical proton irradiation beams based on ultra-intense pulse laser for laying a foundation for the development of a laser-driven proton knife based on miniaturized ultra-short and ultra-intense laser-driven proton accelerator for tumor therapy. Methods The characteristics of medical proton irradiation beams were explored on SILEX-I laser facility. The density and yield of proton beams were measured with nuclear track detector CR39. Moreover, the proton energy spectra and the spatial distributions of proton beams were measured by Thomson magnetic spectrometer and HD810 radiochromic film, separately. Results The spatial profiles of proton beams showed disc-, filament-, and ring-like distributions. The proton beams emitted along the direction of normals to the rear surface of targets within a small cone angle, irrelevant to the direction of incident laser beams. For composite targets, with the same thickness of Al layer, the proton beam flux decreased with the increase of C8H8 layer thickness. The sharp cutoff energy which existed in the proton energy spectra was depended on target thickness and target material. The sharp cutoff energy was decreased with the increase of target thickness. With the same target thickness, the sharp cutoff energy of Al foil target was higher than that of Cu foil target. Conclusion The experiment results provide an important reference for the development of miniaturized laser-driven proton accelerator and tumor radiotherapy.
Last Update: 2019-06-25