Abstract

Info

Title:: Development of cardiac output monitor based on thoracic impedance method

Author(s):: LI Chenyang1; 3; YE Jilun1; 2; 3; ZHANG Xu1; 2; 3; SUN Yang1; 3; LIU Jie1; 3; 1. Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, China; 2. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, China; 3. Shenzhen Key Laboratory of Biomedical Engineering, Shenzhen 518060, China

Keywords:: Keywords: cardiovascular disease; hemodynamic monitoring; cardiac output; thoracic impedance method

Abstract:: Abstract: A system based on thoracic impedance method and adaptive filtering method is developed to realize the real-time monitoring and calculation of hemodynamic parameters such as cardiac output. Firstly, the measurement model and principle of calculating cardiac output by thoracic impedance method are introduced in details; the calculation formula is deduced; and 3 modules for measuring ECG, cardiac impedance and respiration are briefly introduced. Subsequently, the software of the developed system and the design of filtering algorithm are introduced, and the process of adaptive filtering method to eliminate the breathing noise is expounded. Finally, the accuracy between the developed system and Osypka Medical ICON? was compared and validated with the use of the data collected from 20 volunteers. The overall average error of stroke volume is 3.70 mL, with a root mean square error of 6.49 mL; and the overall average error of cardiac output is 0.31 L, with a root mean square error of 0.69 L, which verifies the feasibility of the developed system. The comparison results show that the developed system realizes and verifies the measurements of hemodynamic parameters, such as cardiac output measurement based on thoracic impedance method, with an excellent applicability, but the engineering application of the whole system needs to be further investigated.