Abstract

Info

Author(s):: ZHANG Kunya1; 2; QIAN Xiuqing1; 2; LIU Zhicheng1; 2; 1. School of Biomedical Engineering, Capital Medical University, Beijing 100069, China; 2. Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Beijing 100069, China

Keywords:: ; Keywords: iris; in vivo experiment; material model; finite element method

Abstract:: Abstract: Objective To determine the optimal material model for describing the mechanical responses of the rabbit iris in vivo. Methods Based on the in vivo animal experiments, the finite element model of the anterior segment was established. Three different models, namely linear elastic model, Neo-Hookean model and second-order Ogden model, were taken as the material model of the rabbit iris in vivo. The ranges of material parameters were determined according to related references, and the displacements of the characteristic points were calculated. Based on the results of in vivo experiments, the differences among 3 different models were compared using objective functions. Results The minimum and average values of the objective functions for linear elastic model were the maximum, followed by Neo-Hookean model and second-order Ogden model. Conclusion Among the 3 models, second-order Ogden model is the optimal material model for describing the mechanical responses of the rabbit iris in vivo.