Effects of early transcutaneous acupoint electrical stimulation on postoperative cognition of
elderly patients with hip fractures(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第9期
- Page:
- 1075-1079
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Effects of early transcutaneous acupoint electrical stimulation on postoperative cognition of
elderly patients with hip fractures
- Author(s):
- SUN Ke; LIANG Liping; HU Xiaoxue; WANG Gang
- Department of Anesthesiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou 510080, China
- Keywords:
- transcutaneous acupoint electrical stimulation; hip fracture; postoperative cognitive function; elderly patient
- PACS:
- R312；R683.3
- DOI:
- 10.3969/j.issn.1005-202X.2018.09.015
- Abstract:
- Abstract: Objective To assess the effects of early transcutaneous acupoint electrical stimulation (TAES) on postoperative cognitive
function and inflammatory factors of the elderly with hip fractures. Methods Forty patients aged over 80 years with hip fractures
were randomly divided into control group (group A, 20 cases) and electrical stimulation group (group B, 20 cases). All patients
were treated with spinal-epidural combined anesthesia. Patients in group B received TAES at Baihui (DU20) and fengchi (GB20)
(3 times a day, 30 minutes a time) since 2 days before operation until the operation finished. In group A, the electrodes were only
applied at the corresponding acupoints without electrical stimulation. At admission, and 24, 72 h after finishing operation, all
patients were assessed with MMSE. If the postoperative score was reduced by one standard deviation or more, postoperative
cognitive dysfunction (POCD) was identified. The levels of serum IL-6, IL-10 and S100β proteins were also measured at
admission, the end of operation, and 24, 72 h after finishing operation. Results The incidence of POCD at 24 and 72 h after
finishing operation was 65% (13/20) and 60% (12/20) in group A, higher than 35% (7/20) and 25% (5/20) in group B, with
statistical significance (P<0.05). At all postoperative time points, the levels of serum IL-6, IL-10 and S100β proteins in group
B were significantly lower than those in group A, with statistical significance (P<0.05). Conclusion Early TAES can improve
the postoperative cognitive function of elderly patients with hip fractures and reduce the incidence of POCD, which may be related
to inhibiting the over-expression of serum IL-6, IL-10 and S100β proteins, and reducing the degree of brain injury in patients.
Last Update: 2018-09-28