Abstract

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Title:: Progress of arterial spin labeling perfusion magnetic resonance imaging applied in cognitive impairment

Author(s):: LIU Xiaojun1; OUYANG Yingjun2; WANG Shaosheng3; FANG Suixiong1; CHEN Zhining1; TANG Liang1; CHEN Jie2; ZHOU Jin2; PAN Xiaoping2; 1. Department of Traditional Chinese Medicine, Guangzhou First People’s Hospital, Guangzhou 510180, China; 2. Department of Neurology, Guangzhou First People’s Hospital, Guangzhou 510180, China; 3. Emergency Department, Guangzhou First People’s Hospital, Guangzhou 510180, China

Keywords:: ; Keywords: magnetic resonance imaging; perfusion imaging; arterial spin labeling; cognitive impairment; review

Abstract:: Abstract: Arterial spin labeling perfusion magnetic resonance imaging (MRI) is one of imaging techniques which uses water protons in blood as tracer. Based on the qualitative and quantitative images of cerebral blood flow, arterial spin labeling perfusion MRI can be used for the comparison of the changes in cerebral blood flow perfusion. Besides the advantages of safety, non-invasion, non-radiation, good repeatability and short imaging time, arterial spin labeling perfusion MRI can also achieve whole-brain imaging and assessment of brain functions. Moreover, the technique can be used in perfusion imaging or angiography. With the development of the technique, arterial spin labeling perfusion MRI has been widely used in the study of cerebraovascular disease and tumor. In recent years, the technique has been gradually applied to study cognitive impairment and has made some progress. Herein the progress of arterial spin labeling perfusion MRI in the study of cognitive impairment and its application status are reviewed.