Comparison of the accuracy of bone mineral density measurement by spectral CT vs DXA(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第2期
- Page:
- 194-198
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Comparison of the accuracy of bone mineral density measurement by spectral CT vs DXA
- Author(s):
- DENG Yajun1; 2; HAN Lei3; XIE Qiqi1; 2; LI Wenzhou1; 2; SHI Weidong1; 2; MA Jinglin2; PAN Yunyan3; KANG Xuewen1; WANG Jing1; 2
- 1. Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou 730030, China; 2. Key Laboratory of Bone and Joint Diseases of Gansu Province, Lanzhou 730030, China; 3. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730030, China
- Keywords:
- ; Keywords: spectral computed tomography; dual-energy X-ray absorptiometry; bone density; lumbar vertebrae; ash density
- PACS:
- R318.01；R445.3
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.02.014
- Abstract:
- Abstract: Objective With the ash density of sheep lumbar vertebrae as the standard, to compare the accuracy of spectral computed tomography (CT) and dual-energy X-ray absorptiometry (DXA) for vertebral bone mineral density (BMD) measurement, and to investigate the value of spectral CT in BMD measurement. Methods A total of 36 freshly prepared sheep lumbar vertebrae were selected as the research object. After removing soft tissue around the vertebral body and its attachments, BMD was measured by spectral CT and DXA, and the vertebral body was calcined to obtain the ash density. The BMD values measured by the two methods were compared with ash density, and the correlations between the measured BMD values and ash density were analyzed. Finally, the deviation of BMD measured by energy spectrum CT was compared with the deviation of BMD measured by DXA. Results The difference between measured BMD and ash density was statistically significant (P<0.05). There was a significant correlation between measured BMD and ash density (P<0.05), but the correlation of ash density and BMD measured with spectral CT was higher. The mean deviation of BMD measured by spectral CT was lower than the mean deviation of BMD measured by DXA (0.288 vs 0.372, P<0.05). Conclusion The BMD measured by spectral CT is closer to ash density. Spectral CT is superior to DXA in BMD measurement accuracy and the correction with ash density, which indicates that spectral CT can reflect the changes of BMD more accurately.
Last Update: 2019-02-26