Application of EEG approximate entropy in monitoring the depth of anesthesia(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第1期
- Page:
- 117-120
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
-
Application of EEG approximate entropy in monitoring the depth of anesthesia
- Author(s):
- SU Keyang; ZENG Jingyang; XIE Wenqin; YAN Jingjia; XIE Wenji
- Department of Anesthesiology, Quanzhou First Hospital, Quanzhou 362000, China
- Keywords:
- Keywords: electroencephalogram; approximate entropy; depth of anesthesia; propofol; plasma
- PACS:
- R614.2
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.01.023
- Abstract:
- Abstract: Objective To explore the application of electroencephalogram (EEG) approximate entropy in the monitoring of the depth of anesthesia. Methods Eighty patients who received elective surgery under general anesthesia from January 2017 to January 2018 were enrolled in this study. The bispectral index (BIS) and EEG approximate entropy of all patients were measured before anesthesia, at 5 min after induction, at 60 min after the beginning of surgery and at recovery from anesthesia. With different plasma concentrations of propofol and modified observer’s assessment of alertness/sedation scale (MOAA/S) scores, the changes of BIS value and EEG approximate entropy were analyzed. Finally, Pearson correlation analysis was performed to investigate the correlation of BIS and EEG approximate entropy with the plasma concentration of propofol. Results The BIS value and EEG approximate entropy at 5 min after induction and at 60 min after the beginning of surgery were significantly lower than those before anesthesia (P<0.05), and the values at 60 min after the beginning of surgery were significantly lower than those at 5 min after induction (P<0.05). The BIS value and EEG approximate entropy were negatively correlated with the plasma concentration of propofol (P<0.05). Moreover, statistical differences were found in the EEG approximate entropy when MOAA/S score was 0-1 (P<0.05), but there was no significant difference in BIS value (P>0.05). Conclusion Both EEG approximate entropy and BIS can effectively evaluate the therapeutic effects of propofol, but the former has more advantage in judging the depth of anaesthesia.
Last Update: 2019-01-25